6/17/2025
My lab is primarily focused on both understanding and manipulating cell-ECM mechanotransduction pathways in homeostasis and disease. Our primary interest is in understanding how cells' changing microenvironment direct their phenotype…
6/17/2025
Our group engineers biomaterials to better understand the dynamic interplay between cells and their microenvironment. We apply these platforms to address fundamental human health challenges including: - Treatment of fibrotic diseases -…
6/17/2025
Dr. Christ has a broad interest in muscle physiology, intercellular communication and the role of smooth muscle in the function and dysfunction of visceral and vascular tissues. Dr. Christ's research interests…
6/17/2025
The goal of our laboratory is to understand the genetic mechanisms that lead to increased susceptibility to cardiovascular and metabolic diseases. The interactions among hundreds of genes and gene networks…
6/17/2025
Background and Summary of Previous Findings: Neural development involves competition at many levels, whether it be axons innervating a target or synapses refining a connection. Over 50 years ago, Viktor…
6/17/2025
Our interests focus on developing gene therapy for treating and preventing cardio-vascular disease. An interdisciplinary approach is used to integrate recent technical advances with gene therapy research. In particular, cutting-edge…
6/17/2025
Changes in cellular behavior underlie development, disease, and homeostasis. The response of cells to external factors depends upon the synthesis, degradation, and modification of genes and proteins. These regulated events…
6/17/2025
Advancement in the design of imaging agents has many far-reaching implications for the future directions of molecular imaging and radiological sciences including the following: (1) The early detection of disease…
6/17/2025
Neural regeneration within the central nervous system (CNS) is a critical unmet challenge as CNS disorders continue to be the leading cause of disability nationwide. Engineers can provide a unique…
6/17/2025
Systems analysis has become a requirement for making sense of high-throughput data and for characterizing properties of biological networks. In order to extend these recent developments to medical applications, there…