6/17/2025
Analysis of the role of TGIFs during development. TGIF proteins are transcriptional repressors, which regulate TGFβ signaling and have been suggested to repress retinoid regulated gene expression. Mutations in human TGIF…
6/17/2025
We forge collaborative efforts at the dynamic intersection of biology, chemistry, and medicine, propelling forward the boundaries of scientific exploration. Our work revolves around the development of cutting-edge imaging tools,…
6/17/2025
6/17/2025
My laboratory is interested in understanding the pathogenetic mechanism of Huntington's disease (HD). HD is a dominantly inherited neurodegenerative disorder that affects about 1 in 10,000 people in the United…
6/17/2025
Protein abundance and post-translational modifications (PTMs) are tightly regulated to control cellular activities and developmental processes. Dysregulated protein function, either through abnormal protein levels or PTMs, disrupts normal cellular activities…
6/17/2025
6/17/2025
During the development of chronic lung disease, repetitive environmental insults/injuries, such as cigarette smoke, respiratory viruses infection and allergy lead to ineffective repair in the genetically susceptible subjects. Molecular understanding on…
6/17/2025
Under certain conditions, all essential biopolymers, such as polypeptides, nucleic acids and polysaccharides, have to cross at least one membrane to reach their final destinations. Examples include the secretion of…
6/17/2025
Alloimmunity in Transfusion and Transplantation , Oxidant Stress Biology in Health and Disease
6/17/2025
Research in our laboratory is focused on discovering the mechanisms that control stem cell fate. Specifically, we seek to identify factors that control the progression and branch points of cellular…
