6/17/2025
The central objective of my lab is to understand how the host immune response is reprogrammed by tumors to promote growth and metastasis. Specifically, we focus on the role of…
6/17/2025
Background and Summary of Previous Findings: Neural development involves competition at many levels, whether it be axons innervating a target or synapses refining a connection. Over 50 years ago, Viktor…
6/17/2025
Current funded projects in the laboratory: (1) Elucidation of molecular mechanisms controlling smooth muscle contractility; (2) Development of drugs against the influenza and Ebola viruses; (3) Studies of the mechanism of protein crystallization…
6/17/2025
We study the molecular mechanisms underlying the interaction between pathogens and their mammalian host. In particular, we investigate how the obligate intracellular bacteria Chlamydia trachomatis manipulates the host and establishes…
6/17/2025
Research in the DeSimone laboratory centers on the problem of morphogenesis, which is the process biological systems use to generate form and develop increasingly complex structures needed to carry out…
6/17/2025
Research in the Dolatshahi lab combines multiplex experimental measurements with computational methods (including statistical machine learning, network inference, information theory, signal processing and kinetic-dynamic modeling) to solve problems in the…
6/17/2025
Development of the Cerebral Cortex Your cerebral cortex mediates your conscious sensory perceptions, thoughts, and behaviors. To perform these functions, the cortex must develop the proper structure and circuitry during…
6/17/2025
Our research is focused on the structure and function of macromolecular assemblies, using the techniques of electron cryo-microscopy and three-dimensional reconstruction. Historically, we have been working in two different areas:…
6/17/2025
The research focus in the Elliott Lab is to understand the function of tissue-resident macrophages as effectors of innate immunity in acute and chronic inflammation, and cancer. Macrophages are a…
6/17/2025
Drug Discovery and Molecular Biology of Pathogenic RNA viruses: Ebola, SARS-CoV-2, Influenza and Zika COVID-19, Influenza, Zika fever, and Ebola hemorrhagic fever are diseases caused by highly pathogenic RNA viruses that…
