6/17/2025
Our goal is to understand how the brain integrates sensory feedback to control specific autonomic responses that restore physiologic balance. We are also interested in the cross-talk between cardiorespiratory physiology…
6/17/2025
The Ai lab specializes in protein engineering and employs interdisciplinary approaches, including biophysics, bioanalytical chemistry, chemical biology, synthetic biology, and optical imaging. One of our main areas of focus is the…
6/17/2025
Our lab aims to understand how the brain generates complex electrical signals, and how these signals are used to process information. A major extension of this aim is to understand…
6/17/2025
Infection in the juvenile stage disrupts growth and metabolism, often with long-lasting effects. In young children and in fruit fly larvae, infections disrupt production of homologous hormones: insulin-like growth factor…
6/17/2025
Drug Development Targeting Transcription Drivers in Cancer Dysregulation of gene expression is a hallmark of all cancers. It is critical for self-renewal and chemo-resistance of cancer cells which contributes to…
6/17/2025
The Chalfant Laboratory has historically focused on two major, but diverse areas of basic science in regard to Biochemistry, Biophysics, and Molecular Biology. Specifically, the Chalfant Laboratory studies mechanisms of…
6/17/2025
Current funded projects in the laboratory: (1) Elucidation of molecular mechanisms controlling smooth muscle contractility; (2) Development of drugs against the influenza and Ebola viruses; (3) Studies of the mechanism of protein crystallization…
6/17/2025
In every human cell, dynamic cytoskeletal networks drive or enable critical processes such as cell division, motility, and secretion. Cytoskeletal dysregulation consequently results in cellular malfunction and several pathologies, ranging…
