6/17/2025
Summary: Nano-electromagnetics (NEMS)--Signaling at the nano/bio interface: The measurement, analysis and propagation of electrical, magnetic and optical signals with nanoscale spatial resolution is of interest within biomolecular sensing, morphogenesis, tissue regeneration,…
6/17/2025
The Tang laboratory applies a wide range of approaches such as live-cell imaging, single-cell genomics, and biochemistry to study the mechanisms of complex genome rearrangements in cancers, developmental disorders, and…
6/17/2025
6/17/2025
Myeloid cells, including granulocytes and macrophages, play a crucial role in the body's defense against infections. Abnormalities in their functions and maturation cause various diseases. At the Trinh laboratory, we…
6/17/2025
Papillomaviruses cause the most common lethal malignancy in women world-wide: cervical cancer. Our laboratory studies the actions of the papillomavirus E6 oncoprotein. By identifying host proteins that associate with E6,…
6/17/2025
Research Projects Targeting the intersection of cancer cell-intrinsic signaling and innate immunity The innate immune cells are often suppressed within the tumor microenvironment or co-opted to promote tumor progression and metastasis. Our…
6/17/2025
Our research focus is to understand the structure and function of unusual DNA sequences in living cells, and how these sequences cause genome instability and lead to human diseases. Human…
6/17/2025
The genomic DNA of eukaryotes is packaged into chromatin through a fundamental repeating unit known as the nucleosome. In this chromatin environment, our genomic DNA is constantly exposed to a…
6/17/2025
Despite advancements in melanoma treatment with immune checkpoint blockade (ICB) and BRAF-targeted therapy, 40-65% of metastatic melanoma patients do not survive beyond five years. An observed 'obesity paradox' shows improved…
6/17/2025
How do tissues regenerate after damage? What are the mechanisms that allow cells to coordinate regeneration? The Worley lab combines experimental genetics, developmental biology, and single-cell transcriptomics to uncover the…
