6/17/2025
Basic, autonomous and higher, voluntary cognitive functions of the brain require production of an immense diversity of neuron types at the right place and time, as well as correct wiring…
6/17/2025
The Spencer lab studies host-pathogen interactions of Gram-positive bacteria, focusing on the major neonatal pathobiont Group B Streptococcus (GBS). GBS can asymptomatically colonize the female genital tract, leading to transmission…
6/17/2025
We are interested in understanding how neurons and epithelia develop the asymmetric shapes and subcellular organization, which enable their physiological functions. We focus on cytoskeleton-based mechanisms, and how they malfunction…
6/17/2025
Defects in chromosome segregation can generate aneuploidy, a condition that is found in almost all human tumors and is the major cause of miscarriages and birth defects. The complex process…
6/17/2025
In eukaryotes, approximately 30% of all newly synthesized proteins pass through the endoplasmic reticulum (ER), where they undergo folding and maturation. A significant fraction of nascent proteins may fail to…
6/17/2025
The research in my lab focuses primarily on the cellular mechanisms of implantation and gastrulation in the mouse embryo. In particular , we have been investigating the regulation of motility…
6/17/2025
Agnieszka Swiatecka-Urban studied the regulation of cell-surface stability and intracellular trafficking of membrane proteins in epithelial cells. One focus of her research activity has been the characterization of mechanisms and…
6/17/2025
Our lab studies the structure and function of several membrane proteins of clinical importance in their natural membrane environment. We are also interested in the roles that membrane lipids play…
6/17/2025
The Tang laboratory applies a wide range of approaches such as live-cell imaging, single-cell genomics, and biochemistry to study the mechanisms of complex genome rearrangements in cancers, developmental disorders, and…
6/17/2025
Myeloid cells, including granulocytes and macrophages, play a crucial role in the body's defense against infections. Abnormalities in their functions and maturation cause various diseases. At the Trinh laboratory, we…
