The Genetically Engineered Murine Model (GEMM) Core at UVA provides user-oriented service to efficiently produce and preserve genetically engineered mouse strains for animal model research for investigators at UVA and their collaborators outside UVA. The core’s mission is to support animal model research endeavors, to advance genetic and reproductive technologies for model creation and preservation, and to serve as a resource for design, development and derivation of customized mouse strains.