The Genetically Engineered Murine Model (GEMM) Core at the University of Virginia (UVa) provides user-oriented service to efficiently produce and preserve genetically engineered mouse strains for animal model research for investigators at UVa and their collaborators outside UVa.  The core’s mission is to support transgenic and gene targeting research endeavors, to advance genetic technologies for germline and ES cell manipulations, and to serve as a resource for design, development and derivation of customized mouse strains.

We welcome you to visit our website and explore information about our services.  Please feel free to contact us.  We do CRISPR!  The UVa CRISPR and Transgenic Workshop is held two times a year.  You can register for the Spring or Fall workshop on line.

blastderivedEScolony image_preview blackwhitechimera ZIP1blast
An ES cell colony derived from one explanted blastocyst AP activity detected in undifferentiated NZM 2328 ES cell colonies Black/white chimera made with one of core-derived B6 ES cell lines Blastocysts from a GFP knockin mouse