Scholarly Activity

Recent Publications

Isaac K, Portell CA, Williams ME. The Leukemic Variant of Mantle Cell Lymphoma: An Overview. Current Oncology Reports. 2021 Jul 16;23(9):102
Riley DO, Schlefman JM, Morris AL, Keng MK, El Chaer F. Pegaspargase in Practice: Minimizing Toxicity, Maximizing Benefit. Current Hematologic Malignancy Reports. 2021 May 12:1-1.
Schmidt N, Maitland H. Acute Immune Thrombocytopenia following administration of Shingrix recombinant zoster vaccine. Am J Hematol. 2021 May 1;96(5):E136-E137. doi: 10.1002/ajh.26143. Epub 2021 Mar 11.
Isaac KM, Reed DR, Desai RP, Williams E, Balkrishnan R, Keng MK, Ballen KK. Epidemiology of acute myeloid leukemia in Virginia: Excellent survival outcomes for patients in rural Appalachia. Cancer Reports. 2021 Mar 9:e1354.
Gentzler RD, Riley DO, Martin LW. Striving toward Improved Outcomes for Surgically
Resectable Non-Small Cell Lung Cancer: the Promise and Challenges of Neoadjuvant
Immunotherapy. Current Oncology Reports. 2020 Nov;22(11):1-9.
Zayac AS, Hilliard RW, Olszewski AJ, Pelcovits A, Reagan JL, Hsu A, Riley DO, Austin M, Ollila TA. Enforcing the “4T”: An In-Line Calculator for HIT Antibody Ordering in the Electronic Medical Record. Rhode Island Medical Journal. 2020 Oct 1;103(8):78-83.
Mato AR, Roeker LE, Lamanna N, Allan JN, Leslie L, Pagel JM, Patel K, Osterborg A, Wojenski D, Kamdar M, Huntington SF, Davids MS, Brown JR, Antic D, Jacobs R, Ahn IE, Pu J, Isaac KM, Barr PM, Ujjani CS, Geyer MB, Berman E, Zelenetz AD, Malakhov N, Furman RR, Koropsak M, Bailey N, Hanson L, Perini GF, Ma S, Ryan CE, Wiestner A, Portell CA, Shadman M, Chong EA, Brander DM, Sundaram S, Seddon AN, Seymour E, Patel M, Martinez-Calle N, Munir T, Walewska R, Broom A, Walter H, El-Sharkawi D, Parry H, Wilson MR, Patten PEM, Hernández-Rivas JÁ, Miras F, Fernández Escalada N, Ghione P, Nabhan C, Lebowitz S, Bhavsar E, López- Jiménez J, Naya D, Garcia-Marco JA, Skånland SS, Cordoba R, Eyre TA. Outcomes of COVID-19 in patients with CLL: a multicenter international experience. Blood. 2020 Sep 3;136(10):1134-1143.
Mato A, Roeker L, Jacobs R, Hill BT, Lamanna N, Brander D, Shadman M, Ujjani C, Yazdy MS, Perini G, Pinilla-Ibarz J, Barrientos J, Skarbnik A, Torka P, Pu J, Pagel J, Gohil S, Fakhri B, Choi M, Coombs C, Rhodes J, Barr P, Portell C, Parry H, Garcia C, Whitaker K, Winter A, Sitlinger A, Khajavian S, Grajales-Cruz A, Isaac K, Shah P, Akhtar O, Pocock R, Lam K, Voorhees T, Schuster S, Rodgers t, Fox C, Martinez-Calle N, Munir T, Bhavsar E, Bailey N, Lee J, Weissbrot H, Nabhan C, Goodfriend J, King A, Zelenetz A, Dorsey C, Bigelow K, Cheson BD, Allan JN, Eyre TA. Assessment of the Efficacy of Therapies Following Venetoclax Discontinuation in CLL Reveals BTK inhibition as an Effective Strategy. Clinical Cancer Research. 2020 Jul 15; 26(14): 3589-3596.
Reed DR, Sen J, Pierce E, Elsarrag R, K Keng M. Gilteritinib: An FMS-like tyrosine kinase 3/AXL tyrosine kinase inhibitor for the treatment of relapsed or refractory acute myeloid leukemia patients. J Oncol Pharm Pract. 2020; :1078155220918006
Reed DR, Sen J, Lassiter K, Thomas T, Harr E, Daniels E, Keng M. Prospective Initiative to Reduce Mucosal Barrier Injuries and Bloodstream Infections in Patients With Hematologic Malignancy Receiving Inpatient Chemotherapy. JCO Oncol Pract. 2020 Mar;16(3):e306-e312.
Isaac K, Mato AM. Acalabrutinib and its therapeutic potential in the treatment of Chronic Lymphocytic Leukemia: a short review on emerging data. Cancer Management and Research. 2020 Mar 5; 2020(12): 2079 – 2085.
Shantzer L, Davidson K. Bite Cells Abound. The Hematologist. 2020 Mar 1;17(2).
McLoughlin EM, Larner JM, Bergman MP, Stelow EB, Brady K, Lynch AC, Abraham S, Gentzler RD. Rapid Response to Pembrolizumab in a Critically Ill Mechanically Ventilated Patient with New Diagnosis of Non- Small Cell Lung Cancer (NSCLC). Journal of Thoracic Oncology. 2019 Sep;14(9):e193-e195. PMID: 31445732
Mort M, Sen J, Morris A, DeGregory A, McLoughlin EM, Mort J, Dunn S, Abuannadi M, Keng M. Evaluation of Cardiomyopathy in Acute Myeloid Leukemia Patients Treated with Anthracyclines. Journal of Oncology Pharmacy Practice. 2019 Sep 9:1078155219873014.
Reed DR, Elsarrag RZ, Morris AL, Keng MK. Enasidenib in acute myeloid leukemia: clinical development and perspectives on treatment. Cancer Manag Res. 2019;11:8073-8080.
Reed DR, Pierce EJ, Sen JM, Keng MK. A prospective study on urine alkalization with an oral regimen consisting of sodium bicarbonate and acetazolamide in patients receiving high-dose methotrexate. Cancer Manag Res. 2019;11:8065-8072.
Man L, Sen J, Giordano J, McLoughlin EM, Morris A, DeGregory K, Thomas T, Daniels E, Huntsinger, Keng M,. A multidisciplinary effort to decrease time from admission to chemotherapy on an inpatient oncology unit. Journal of Oncology Practice. 2019 Aug;15(8):e728-e732.
McLoughlin EM, Fadul CE, Patel SH, Hall RD, Gentzler RD. Clinical and Radiographic Response of Leptomeningeal and Brain Metastases to Encorafenib and Binimetinib in a patient with BRAF V600E- mutated Lung Adenocarcinoma. Journal of Thoracic Oncology. July 2019.

Recent Abstracts/Presentations

Jones C, Riley DO, Morris A, Sen JM, Ferrari A, Humphrey J, VanHoose J, Schmidt N, Schlefman J, El Chaer F, & Keng MK. Reducing length of stay for patients with acute myeloid leukemia receiving inpatient high-dose cytarabine consolidation chemotherapy. ASCO Quality Care Symposium. September 24-25, 2021.
Riley DO, Kaur N, Baglione A, Hall RD, Barnes L, & Gentzler RD. Adverse event burden of oral
tyrosine kinase inhibitors in EGFR and ALK metastatic non-small cell lung cancer. IASLC World Conference on Lung Cancer. September 8-14, 2021.
Riley DO, Abraham RS, Alaklabi SF, Devitt ME, Hall RD, Horton BJ, & Gentzler RD. CNS adverse events and survival in patients with NSCLC brain metastases treated with concurrent radiation and immunotherapy. IASLC World Conference on Lung Cancer. September 8-14, 2021.
Sawalha Y, Goyal S, Switchenko JM, Romancik JT, Kamdar M, Greenwell IB, Hess BT, Isaac K, Portell CA, Mejia Garcia AV, Goldsmith SR, Grover NS, Riedell PA, Karmali R, Burkart M, Buege MJ, Akhtar OS, Torka P, Kumar A, Hill BT, Kahl BS, Cohen JB. Outcomes of Patients with Relapsed Mantle Cell Lymphoma Treated with Venetoclax: A Multicenter Retrospective Analysis. American Society of Hematology Annual Meeting, December 2020.
Larose MI, Bair SM, Manjunath S, Carter J, Evens AM, Isaac K, Portell CA, Chowdhury S, Epperla, N, Intrator J, Feldman TA, Saeed H, Isenalumhe L, Landsburg DJ, Nasta SD, Gerson JN, Barta SK, Chong EA, Schuster SJ, Paydar I, Plastaras J, Svoboda J. Radiation-Based Approaches as an Alternative to Stem Cell Transplant for Relapsed/Refractory Classical Hodgkin Lymphoma: A Multicenter Retrospective Analysis. American Society of Hematology Annual Meeting, December 2020.
Reed DR, Wang J, Elsarrag R, Isaac KM, Keng MK. Body Mass Index and Outcomes in Acute Myeloid Leukemia. American Society of Hematology Annual Meeting, December 2020.
Jayappa KD, Farrington C, Gordon VL, Saha S, Morris C, Isaac KM, Bender TP, Williams ME, Portell CA, Narla G, Weber MJ. Modulation of the Tumor Suppressor Protein PP2A Using a Small Molecule Agonist Overcomes Multi-Drug Resistance through Mitochondrial Permeability Transition Pore (MPTP) Dependent Induction of Apoptosis in Chronic Lymphocytic Leukemia. American Society of Hematology Annual Meeting, December 2020.
Young P, Mock J, Wynter E, Elghawy O, Sytov A, Gentzler R, Hall R. Effect of opioids on efficacy of immunotherapy in metastatic non-small cell lung cancer. Carey, Marshall, Thorner Scholar’s and Research Day. Charlottesville, VA. May 2020.
Bollam R, Mock J, Lu H, Kaur V. Incidence of CNS Metastasis in metastatic melanoma patients following immunotherapy. Carey, Marshall, Thorner Scholar’s and Research Day. Charlottesville, VA. May 2020
Pooja Mehra, Surabhi Palkimas, Laura Parsons, Theresa Libby, Leslie Ward, Christian Chisholm, Kelly Mercer Davidson; Multidisciplinary Implementation of an Iron Deficiency Anemia in Pregnancy Treatment Protocol. Blood 2019; 134 (Supplement_1): 2121.
Anthony R. Mato, Lindsey E. Roeker, Toby A. Eyre, Ryan Jacobs, Brian T. Hill, Nicole Lamanna, Danielle M. Brander, Mazyar Shadman, Chaitra Ujjani, Maryam Yazdy, Guilherme Fleury Perini, Javier Pinilla Ibarz, Jacqueline C Barrientos, Alan Skarbnik, Pallawi Torka, Jeffrey J Pu, John M. Pagel, Satyen Gohil, Bita Fakhri, Michael Y. Choi, Catherine C. Coombs, Joanna Rhodes, Paul M. Barr, Craig A. Portell, Helen Parry, Christine Ann Garcia, Kate J Whitaker, Allison M. Winter, Andrea Sitlinger, Sirin Khajavian, Ariel F Grajales-Cruz, Krista Isaac, Pratik Shah, Othman S. Akhtar, Rachael Pocock, Kentson Lam, Timothy J Voorhees, Stephen J. Schuster, Thomas David Rodgers, Nicolas Martinez-Calle, Talha Munir, Erica B Bhavsar, Neil Bailey, Jason C. Lee, Hanna Weissbrot, Chadi Nabhan, Julie Goodfriend, Amber C. King, Andrew D. Zelenetz, Colleen Dorsey, Kayla Bigelow, Bruce D. Cheson, Christopher P Fox, John N. Allan; Efficacy of Therapies Following Venetoclax Discontinuation in CLL: Focus on B-Cell Receptor Signal Transduction Inhibitors and Cellular Therapies. Blood 2019; 134 (Supplement_1): 502.
Victor M. Orellana-Noia, Krista Isaac, Nolan A Wages, Mary-Kate Malecek, Nancy L. Bartlett, Timothy J Voorhees, Natalie S Grover, Steven R. Hwang, N. Nora Bennani, Rachel Hu, Brian T. Hill, Eric Mou, Ranjana H Advani, Jordan Carter, Kevin A. David, Hatcher J. Ballard, Jakub Svoboda, Gabriela Magarelli, Tatyana A. Feldman, Michael C. Churnetski, Jonathon B. Cohen, Andrew M. Evens, Craig A. Portell; Fitness and Anthracycline Use in Front-Line Therapy for Older Patients with Classical Hodgkin Lymphoma: A US Multi- Center Retrospective Analysis. Blood 2019; 134 (Supplement_1): 4027.
Andrew M. Evens, Alexey Danilov, Deepa Jagadeesh, Amy Sperling, Seo-Hyun Kim, Ryan Vaca, Catherine Wei, Daniel Rector, Suchitra Sundaram, Nishitha Reddy, Yong Lin, Umar Farooq, Christopher D’Angelo, David A. Bond, Stephanie Berg, Michael C. Churnetski, Amandeep Godara, Nadia Khan, Yun Kyong Choi, Maryam Yazdy, Emma Rabinovich, Gaurav Varma, Reem Karmali, Agrima Mian, Jeremy Ramdial, Madelyn Burkart, Peter Martin, Albert Ren, Ayushi Chauhan, Catherine Diefenbach, Allandria Straker-Edwards, Andreas Klein, Kristie A. Blum, Kirsten M Boughan, Scott E. Smith, Brad M. Haverkos, Victor M. Orellana- Noia, Vaishalee P. Kenkre, Adam Zayac, Seth M Maliske, Narendranath Epperla, Parameswaran Venugopal, Tatyana A. Feldman, Stephen D. Smith, Andrzej Stadnik, Izidore S. Lossos, Kevin A. David, Seema Naik, Paolo Caimi, Manali Kamdar, Craig A. Portell, Adam J Olszewski, Juan Pablo Alderuccio; The Evaluation and Treatment (Tx) of Burkitt Lymphoma (BL) in the Modern Era: Real World (RW) Outcomes and Prognostication across 26 US Cancer Centers (CC). Blood 2019; 134 (Supplement_1): 397.
Adam Zayac, Andrew Matthew Evens, Andrzej Stadnik, Stephen D. Smith, Deepa Jagadeesh, Lori A. Leslie, Catherine Wei, Seo-Hyun Kim, Seema Naik, Suchitra Sundaram, Nishitha Reddy, Umar Farooq, Vaishalee P. Kenkre, Narendranath Epperla, Kristie A. Blum, Nadia Khan, Daulath Singh, Juan Pablo Alderuccio, Amandeep Godara, Maryam Yazdy, Catherine Diefenbach, Emma Rabinovich, Gaurav Varma, Reem Karmali, Yusra Shao, Asaad Trabolsi, Madelyn Burkart, Peter Martin, Sarah Stettner, Ayushi Chauhan, Yun Kyong Choi, Allandria Straker-Edwards, Andreas Klein, Michael C. Churnetski, Kirsten M Boughan, Stephanie Berg, Brad M. Haverkos, Victor M. Orellana-Noia, Christopher D’Angelo, David A. Bond, Seth M Maliske, Ryan Vaca, Gabriela Magarelli, Amy Sperling, Max J. Gordon, Kevin A. David, Paolo Caimi, Manali Kamdar, Craig A. Portell, Parameswaran Venugopal, Izidore S. Lossos, Adam J Olszewski; Outcomes of Patients with Newly- Diagnosed Burkitt Lymphoma (BL) and Central Nervous System (CNS) Involvement Treated in the Modern Era: A Multi-Institutional Real-World Analysis. Blood 2019; 134 (Supplement_1): 402.
Isaac K, Reed DR, Desai RP, Williams E, Balkrishnan R, Keng MK, Ballen K. Distance Does Not Matter: Excellent Survival Outcomes for Leukemia Patients in Rural Appalachia. Poster Presentation, 2019 American Society of Hematology Annual Meeting; Blood 2019; 134: 4784
Earasi, A.G., Figueroa, E.J., Mehra, P., Baray, M., Crawford, M.P., Hall, R.D., & Behm, B.W. (2019). Immunotherapy-Mediated Hemorrhagic Gastritis after Ipilimumab and Nivolumab Therapy: 2734. The American Journal of Gastroenterology, 114.
Moore M, Hall R, McLoughlin EM, Melson J, Horton B, Mills A, Gentzler RD. Overall Survival by IDO1 and PD-L1 Expression in NSCLC Patients Receiving an Immune Checkpoint Inhibitor (ICI). IASLC World Lung Conference, Barcelona, Spain. Accepted for Poster Presentation (Abstract #1952). September 2019.
McLoughlin EM, Hanson L, Moore M, Horton B, Gentzler RD, Hall R. Clinical Characteristics and Outcomes in NSCLC Patients Associated with Very High PD-L1 Expression. IASLC World Lung Conference, Barcelona, Spain. Poster Presentation (Abstract #1787). September 2019.