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Kibbe-Tsihlis Lab

RESEARCH

Kibbe-Tsihlis V lab logoDrs. Kibbe and Tsihlis have received funds from the National Institutes of Health, the American Heart Association, the Department of Defense, the Department of Veterans Affairs, the American Medical Association, and various intramural sources. The following are areas of active research in our laboratory:

  • Generate nanoscale therapies to prevent non-compressible torso hemorrhage

  • Synthesize biocompatible, elastomeric, polymer-based customizable stents

  • Implement new atraumatic therapies to remove atherosclerotic plaque

  • Develop and evaluate innovative, systemically-delivered, targeted nano therapies to prevent restenosis, atherosclerosis, and smoke-induced acute lung injury

  • Design and characterize novel NO-releasing films, gels, and prosthetic materials

  • Understand how NO regulates the ubiquitin-proteasome pathway

  • Create sustainable long-term release of NO for in vivo therapies

  • Evaluate NO-based therapies in diabetes and metabolic syndrome

  • Determine the role sex and hormones play on the effects of therapies in the vasculature

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