9/29/2022
IL-1R drives acute disease tolerance, liver and skeletal muscle fibrosis, and sustained cachexia during T. gondii infection Advisor: Ewald, Sarah, MD-MICR Microbiology, University of Virginia Abstract: Toxoplasma gondii (T. gondii)…
9/29/2022
Diacylglycerol Kinase α is a Pharmacologically Targetable Immune Regulator with a Newly Identified Role in Macrophage Activation Advisor: Purow, Benjamin, MD-NEUR Neurology UPG-MD-NEUR Neurology, University of Virginia Abstract: The diacylglycerol…
9/29/2022
Characterization of Papillomavirus E6 Proteins that Bind Cellular E6AP Advisor: Vande Pol, Scott, MD-PATH Research, University of Virginia Abstract: Papillomaviruses infect vertebrate epithelia and induce squamous papillomas in order to…
9/29/2022
Understanding the Role of the Lymphatic Vasculature in Chemotherapeutic Efficacy and Cancer Progression Advisor: Munson, Jennifer, Department of Biomedical Engineering, University of Virginia Abstract: Despite advances in targeted therapies, cytotoxic…
9/29/2022
Perivascular Cell Differentiation in Tissue Remodeling and Fibrosis Advisor: Peirce-Cottler, Shayn, MD-BIOM Biomedical Eng, University of Virginia Barker, Tom, EN-Biomed Engr Dept, University of Virginia Abstract: Perivascular cells, or pericytes,…
9/29/2022
Regulation of cellular metabolism in tumor infiltrating CD8+ T cells and its role in their dysfunction Advisor: Bullock, Timothy, MD-PATH Research, University of Virginia Abstract: Tumor infiltrating CD8+ T cells…
9/29/2022
Glucosylceramide Maintains Influenza Infection through Regulation of Cellular Endocytosis Advisor: Kester, Mark, MD-PHAR Pharmacology, University of Virginia Abstract: Influenza is an enveloped negative sense RNA virus encapsulated in a lipid…
Pedro Filipe Da Costa Pinheiro, PhD, 2021
9/29/2022
Sphingolipids and Prostate Cancer: complex molecules for a complex disease Advisor: Kester, Mark, MD-PHAR Pharmacology, University of Virginia Abstract: Prostate cancer (PCa) is the second most incident cancer in men…
9/29/2022
RNA Polymerase I Inhibition in Ovarian Cancer Advisor: Landen, Charles, MD-OBGY Gyn Oncology UPG-MD-OBGY Gyn Oncology, University of Virginia Abstract: Ovarian cancer is the fifth leading cancer killer of women…
9/29/2022
Toward better immunotherapy for glioblastoma:Technical choices for preclinical studies and a novel treatment strategy Advisor: Purow, Benjamin, MD-NEUR Neurology, University of Virginia Abstract: Glioblastoma (GBM) is a Grade 4 brain…