Wages, Nolan A., Ph.D.

Nolan Wages.JPGDr. Wages is an Associate Professor in the Division of Translational Research & Applied Statistics in the Department of Public Health Sciences, and an active member of the UVA Cancer Center Biostatistics Shared Resource. As a member of this division, Dr. Wages is part of a national research effort to change the way early phase trials in oncology are done, not only through the pursuit of novel statistical methods, but also by focusing on successful implementation of innovative methods into real studies. He works with investigators in the UVA Cancer Center to refine early phase research objectives and to tailor designs to meet those objectives.

Associate Professor
Translational Research & Applied Statistics
Ph.D., Statistics, University of Virginia, 2010

P.O. Box 800717
Tel: 1-434-924-8222
Fax: 1-434-243-5787
Email: nwages@virginia.edu
West Complex Old Med School Room 3894

Research Interests:

  • Design, monitoring, and analysis of early phase clinical trials in oncology.

Professional Service:

  • Associate Editor, Clinical Trials
  • Faculty member, ASCO/AACR Methods in Clinical Cancer Research Workshop; Vail, CO
  • ASCO Conquer Cancer Foundation Grants Selection Committee, Young Investigator Award Review Panel

Teaching Responsibilities:

  • Introduction to Statistics lecture, Foundations of Medicine for incoming medical students
  • Introduction to Biostatistics, Short course for Radiation Oncology residents and Hematology Oncology fellows

Additional Resources:

Selected Publications:

  1. Hobbs B, Barata P, Kanjanapan Y, Paller C, Perlmutter J, Pond GR, Prowell T, Rubin E, Seymour L, Wages NA, Yap T, et al. Seamless designs: current practice and considerations for early phase drug development in oncology. J Natl Cancer Inst 2019; 111(2): djy196. PMID: 30561713.
  2. Wages NA, Chiuzan C, Panageas KS. Design considerations for early-phase clinical trials of immune-oncology agents. J Immunother Cancer 2018; 6: 81. PMCID: PMC6103998.
  3. Wages NA, Portell CA, Williams ME, Conaway MR, Petroni GR. Implementation of a model-based design in a phase 1b study of combined targeted agents. Clin Cancer Res 2017; 23: 7158-64. PMCID: PMC5712236.
  4. Wages NA, Slingluff CL, Jr, Petroni GR. Statistical controversies in clinical research. early-phase adaptive design for combination immunotherapies. Ann Oncol 2017; 35: 696-701. PMID: 28011450.
  5. Wages NA, Conaway MR, O’Quigley J. Continual reassessment method for partial ordering. Biometrics 2011; 67: 1555-63. PMCID: PMC3141101.

                 Full list of Publications