Zhu, Hong, Ph.D.

Hong Zhu, Ph.D., is a tenured Professor of Biostatistics in the Department of Public Health Sciences at the University of Virginia (UVA) School of Medicine. She currently serves as Director of Biostatistics Shared Resource (BSR) of the UVA Comprehensive Cancer Center. Prior to joining UVA in November 2022, she was on faculty at the University of Texas Southwestern Medical Center from 2013 to 2022 and at the Ohio State University College of Public Health from 2010 to 2013.

Dr. Zhu’s methodological research interests include design and analysis of explanatory and pragmatic clinical trials, statistical methods for complex survival data (biased sampling, semi-competing risks, multivariate survival data), and causal inference. Her work is inspired by and applied to biomedical and clinical studies. Dr. Zhu’s collaborative research interests include basic, clinical, translational, and population sciences studies in areas including cancer, chronic and infectious diseases. Dr. Zhu has published multiple high-impact statistical methodology papers and co-authored a book entitled “Design and Analysis of Pragmatic Trials” (Chapman & Hall/CRC, 2023).

Dr. Zhu’s research work has been supported by extramural funding. She is the PI of a PCORI Methodology Award to improve methods for design and analysis of comparative effectiveness research (CER) with complex observational healthcare data, and the PI of an NSF Award to develop a dynamic modeling framework and risk prediction tool with complex observational semi-competing risks data. She serves as Biostatistics and Data Management Core Co-Director of an NIH P20 SPORE Planning Award on cancer health disparities, and a co-investigator on multiple large federally or state funded grants.

Dr. Zhu frequently serves as a standing member or ad hoc reviewer of NIH study sections and PCORI review panels. She is a statistical member on the UVA Cancer Center’s Protocol Review Committee. She currently serves on the editorial board for BMC Cancer and is a committee member of NCI Head and Neck Cancer Steering Committee Metastatic-Recurrent Task Force.

Professor of Biostatistics
Director of Cancer Center Biostatistics Shared Resource

Ph.D., Biostatistics, Johns Hopkins University Bloomberg School of Public Health, 2010
B.Sc., Statistics, University of Science and Technology of China, 2005

P.O. Box 800717
Charlottesville, VA 22908-0717
Tel: 1-434-297-7876
Email: hzhu2m@virginia.edu
Old Med School, Room 3874


Survival analysis, Clinical trial design and analysis, Causal inference

Research Interests:

  • Analysis of Complex Survival Data
  • Design and Analysis of Explanatory and Pragmatic Clinical Trials
  • Causal Inference, Comparative Effectiveness Research (CER)
  • Observational Studies using Real-World Data
  • Cancer Control, Risk Prediction, Health Outcomes Research


A complete list of published work is available at MyBibliography and Google Scholar.