Search

People

Group picture with Pei-Chi, Britney, Yuh-Hwa, Anna, Heather, and Kyubin

Principal Investigator

Pronouns: She/Her/Hers

Yuh-Hwa received her BS degree from National Taiwan University, and PhD from North Carolina State University studying translational control of ferritin protein with Elizabeth Theil. Her postdoctoral training was on electron microscopy of nucleic acid/protein interactions with Jack Griffith at UNC-Chapel Hill. She joined UVA in 2014. Her research focuses on understanding how unusual DNA sequences/structures behave in human cells, and their role in human diseases. She enjoys working with graduate students, and loves gardening, exploring nature, and dining with friends.

Contact

Dr. Yuh-Hwa Wang

Current Members

Anna Bartosik
Graduate Student
Pronouns: She/Her/Hers

Anna earned her BS and MS in Biochemistry from Jagiellonian University in Krakow, Poland, studying DNA double-strand breaks using confocal microscopy, and on histone H1 protein and chromatin changes in living cells upon non-covalent interaction of small molecules with the DNA. She has joined the Wang lab to work on the roles of fragile sites in gene rearrangements in lung and breast cancer. With the help of all lab members, she’s been successfully gaining knowledge and practical laboratory skills. Besides science, Anna enjoys cooking and outdoor activities like running and hiking.

Anna, smiling, holding tube

Pei-Chi Hou
Research Scientist
Pronouns: She/Her/Hers

Pei-Chi’s project is to study DNA secondary structure-mediated DNA double strand break (DSB) in genome instability in cancer. She earned her Ph.D. degree from Institute of Basic Medical Sciences, National Cheng Kung University, Taiwan, and worked on the mechanism of hypoxia and tumor microenvironment involved cancer stemness and metastasis. Prior to the journeys to Dr. Wang’s lab, she was studying the functionality of single nucleotide polymorphisms in Idiopathic Pulmonary Fibrosis and the impacts of genetic mutations in small cell lung cancer when she was Research Associate. Besides the broad knowledge and practices on science, she has good skills on communication, problem-solving, and the most important, the ability to work as a team.

Pei-Chi, smiling, spinning samples

Kyubin Lee
Ph.D., Postdoctoral Research Associate
Pronouns: He/Him/Hiss

Kyubin received his B.S. in Mathematics and Ph.D. in Computer Science from the University of Wisconsin-Madison. His Ph.D. research with Mark Craven focused on developing explainable machine learning (ML) methods with applications to mapping viral genotypes to host disease phenotypes. His postdoctoral training was on developing computational methods for cancer genomics research at National Cancer Center in South Korea as part of his military service. He joined Wang’s lab in 2022, and with the help of all lab members he has enjoyed learning various features of DNA structure-driven fragility. He is interested in applying integrative ML methods to address challenges in this new research field. Outside of research, he enjoys spending time with his family.

Kyubin smiling

Britney Doan
Undergraduate Student
Pronouns: She/Her/Hers

Britney Doan is in her fourth year at UVA studying biochemistry. She is currently studying variants in DNA breaks in breast cancer cells to ascertain if certain variants can change the DNA secondary structure in therapy-related AML. While in this lab, she has been learning a variety of lab techniques and gaining knowledge on the world of research. In her free time, she likes to cook and paint.

Britney, concentrated, pipeting

Rishi Vuppala
Undergraduate Student
Pronouns: He/Him/His

Rishi Vuppala is in his third year at UVA studying biochemistry. He is currently studying the role of rDNA breakage in aging to identify specific genes and pathways that may lead to the accumulation of DSB that causes cancer and leads to aging. In his free time, he likes to play basketball and hang out with friends.

Rishi pipetting

Alumni

Heather Raimer Young, Ph.D.Heather Raimer loading a small sequencing gel
Reem Al-Humadi, UndergraduatePicture of Reem Al-Humadi
Naomi Atkin, Ph.D.Naomi Atkin loading a large sequencing gel

Sandeep Singh, Ph.D., Postdoc AssociateSandeep Singh sitting in front of two computer screens
Laurey Comeau, Lab TechnicianLaurey Comeau checking cells with a microscope

Andrew Dudzik, UndergraduateAndrew Dudzik sitting in front of the electrophoresis gel imager

Karol Szlachta, Ph.D. Postdoctoral FellowKarol Szlachta sitting in front of a computer monitor
Arkadi Manukyan, Ph.D. Postdoctoral FellowArkadi Manukyan sitting in front of a microscope

Christine Tran, Undergraduate Researcher
Arthur Willmore, Undergraduate Researcher
Christine Lehman, Ph.D., Postdoctoral Research Fellow
Gagan Gupta, Undergraduate Researcher
Matthew Given, Summer Medical Student
Anita Salamon, Visiting Master’s Student
Roberta Lynn Turner, Ph.D., Postdoctoral Research Fellow
Maddy Carmain, Summer Medical Student
Julianna Marotta, Summer Undergraduate Research Student
Ryan Thys, Ph.D.
Laura Dillon, Ph.D.
Allison Weckerle, Ph.D.
Cheng Wang, Ph.D.
Lindsay Holder
Madhumita Santra, Ph.D.