People

Pronouns: She/Her/Hers

Yuh-Hwa received her BS degree from National Taiwan University, and PhD from North Carolina State University studying translational control of ferritin protein with Elizabeth Theil. Her postdoctoral training was on electron microscopy of nucleic acid/protein interactions with Jack Griffith at UNC-Chapel Hill. She joined UVA in 2014. Her research focuses on understanding how unusual DNA sequences/structures behave in human cells, and their role in human diseases. She enjoys working with graduate students, and loves gardening, exploring nature, and dining with friends.

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Anna Bartosik
Graduate Student
Pronouns: She/Her/Hers

Anna earned her BS and MS in Biochemistry from Jagiellonian University in Krakow, Poland, studying DNA double-strand breaks using confocal microscopy, and on histone H1 protein and chromatin changes in living cells upon non-covalent interaction of small molecules with the DNA. She has joined the Wang lab to work on the roles of fragile sites in gene rearrangements in lung and breast cancer. With the help of all lab members, she’s been successfully gaining knowledge and practical laboratory skills. Besides science, Anna enjoys cooking and outdoor activities like running and hiking.

Pei-Chi’s project is to study DNA secondary structure-mediated DNA double-strand break (DSB) in genome instability in cancer. She earned her Ph.D. from the Institute of Basic Medical Sciences, National Cheng Kung University, Taiwan. She worked on the mechanism of hypoxia and tumor microenvironment involving cancer stemness and metastasis. Before the journey to Dr. Wang’s lab, she was studying the functionality of single nucleotide polymorphisms in Idiopathic Pulmonary Fibrosis and the impacts of genetic mutations in small-cell lung cancer when she was Research Associate. Besides the broad knowledge and practices in science, she has good skills in communication, problem-solving, and most important, the ability to work as a team.

Kyubin received his B.S. in Mathematics and Ph.D. in Computer Science from the University of Wisconsin-Madison. His Ph.D. research with Mark Craven focused on developing explainable machine learning (ML) methods with applications to mapping viral genotypes to host disease phenotypes. His postdoctoral training was on developing computational methods for cancer genomics research at the National Cancer Center in South Korea as part of his military service. He joined Wang’s lab in 2022, and with the help of all lab members, he has enjoyed learning various features of DNA structure-driven fragility. He is interested in applying integrative ML methods to address challenges in this new research field. Outside of research, he enjoys spending time with his family.

Will Marschall is in his second year at UVA studying biomedical engineering. He is currently studying the impact of gene expression on DNA topoisomerase II inhibition. While in this lab, he has been learning various lab techniques and gaining knowledge on the world of research. In his free time, he likes to read and climb.