Woodfolk, Judith A.

Judith A. Woodfolk

Judith A. Woodfolk

Primary Appointment

Associate Professor, Medicine: Allergy and Clinical Immunology

Education

  • PhD, Microbiology, University of Virginia
  • MD, Medicine, Sheffield University
  • MBChB, Medicine, Sheffield University

Contact Information

MR-4, 5061
Charlottesville, VA 22908
Telephone: 434-924-1293 / 434-982-3958
Fax: 434-924-1251
Email: jaw4m@virginia.edu

Research Interests

Cellular mechanisms of allergic disease in humans.

Research Description

My research is driven by theories which challenge current concepts, and by novel ideas, related to the role of T cells, dendritic cells and basophils in allergic disease. The primary objective of my work is to gain new insight into cellular mechanisms that initiate and promote allergic responses in humans. My foray into cellular immunology began during my thesis work which focused on defining major T cell epitopes of allergens in humans.

Current projects include: (1) analysis of the role of effector and regulatory T cells in severe allergic disease; (2) cellular and molecular studies on the role of TSLP and its receptor in allergic disease; (3) investigation of the role of extracellular matrix molecules in atopic dermatitis; and (4) immune mechanisms of rhinovirus-induced asthma exacerbations. Our work involves a high degree of collaboration with clinical specialists in adult and pediatric allergy and pediatric respiratory medicine, as well as with basic scientists in the fields of murine immunology, virology, biochemistry, genetics, epigenetics, and molecular biology. By focusing on human-based systems, we aim to accelerate the transition of experimental findings from the bench to the bedside.

Selected Publications