Dr. Oluwaseun (Musty) Mustapha

Office Location: Pinn 4017

Email: vqq6av@virginia.edu

Oxidative stress has been clearly linked with Alzheimer’s disease. Elucidating the molecular mechanisms underpinning the pathogenesis of this disease is crucial for developing new therapies. Genetically encoded redox biosensors allow for visualization of molecular pathways in both in vivo and in vitro studies. I am seeking to deploy these biosensors in uncovering the molecular mechanisms involved in Alzheimer’s disease. When not in the lab, I enjoy reading and watching soccer.

Current position:

Research Associate 04/2024 – present

Previous Education and Professional Experiences:

Ph.D. Neurobiology 09/2014 – 02/2021

Department of Veterinary Anatomy, University of Ibadan, Nigeria

Thesis title: “Developmental Biology, and Neurogenesis in the Prenatal African Greater Cane Rat (Thryonomys swinderianus, Temminck)”

MSc. Veterinary Anatomy 01/2011 – 04/2014

Department of Veterinary Anatomy, University of Ibadan, Nigeria

Thesis title: “Behavioural and neurocellular effects of vanadium on neonatal mice”

Doctor of Veterinary Medicine (DVM) 09/2000 – 06/2007

University of Ibadan, Nigeria

Representative Publications:

Olopade, JO, Mustapha, OA, Fatola, IO, Ighorodje E, Folarin, OR, Olopade FE, Omile I.C, Obasa AA, Oyagbemi, A.A, Olude MA, Thackray AM & Bujdoso R (2023). Neuropathological profile of the African Giant Rat brain (Cricetomys gambianus) after natural exposure to heavy metal environmental pollution in the Nigerian Niger Delta. Environmental Science and Pollution Research 30:120496–514. https://doi.org/10.1007/s11356-023-30619-0

Oluwaseun Mustapha, Thomas Grochow, James Olopade and Simone A. Fietz (2023). Neocortex neurogenesis and maturation in the African greater cane rat. Neural Development 18(1):7. https://doi.org/10.1186/s13064-023-00175-x.

Mustapha O.A., Awala-Ajakaiye M., Taiwo B., Bello S.T., Olude M.A., Olopade J.O. (2023). Vanadium impairs neuronal infrastructure of the hippocampal trisynaptic loop in the African Giant Rat (Cricetomys gambianus, Waterhouse). Nigerian Journal of Neuroscience 14(1):1-9. http://doi.org/10.47081/njn2023.14.1/001.

Olude MA, Mouihate A, Mustapha OA, Farina C, Quintana FJ and Olopade JO (2022). Astrocytes and Microglia in Stress-Induced Neuroinflammation: The African Perspective. Frontiers in Immunology 13:795089. https://doi.org/10.3389/fimmu.2022.795089.

Mustapha O.A., Ezekiel O.S., Olaolorun F., Awala-Ajakaiye M., Popoola E.S., Olude M.A., and Olopade J.O (2020). Morphological Characterization of the Developing Greater Cane Rat (Thryonomys swinderianus) Brain. Developmental Neuroscience, 42(2-4):114-123. https://doi.org/10.1159/000510848.

Mustapha O.A., Olude M.A., Bello S.T., Taiwo A.I., Jagun A., Olopade J.O. (2019). Peripheral axonopathy in sciatic nerve of adult wistar rats following exposure to vanadium. Journal of Peripheral Nervous System, 24:94–99. https://doi.org/10.1111/jns.12294.

For all publications, see Google Scholar: https://scholar.google.com/citations?user=OEU6Cu4AAAAJ&hl=en