Bayliss Lab
Welcome to the Bayliss Laboratory Website
At the most basic level, our laboratory is interested in how signaling in the brain controls behavior. In particular, we study how brain cell activity is regulated by neurotransmitters and their receptors, signaling pathways and ion channel effectors. Our current research focuses on: a) signaling mechanisms that mediate control of breathing by CO2; and b) mechanisms that activate membrane channels that themselves mediate release of signaling molecules. This work spans from biophysical examination of individual molecules to physiological studies of animal behavior.
Receptor in the Brain Controls BreathingLearn MoreControl of breathing in mammals depends primarily not on sensing oxygen, but rather on detecting concentrations of carbon dioxide in the blood.
Unexpected Link Between an Antibiotic, Pannexin Channels, and ApoptosisLearn MoreA novel linkage between an antibiotic, pannexin channels, and cellular integrity.
Identification of a Novel Mitochondrial Uncoupler That Does Not Depolarize the Plasma MembraneLearn MoreThe pharmacological uncoupling for the treatment of the myriad of diseases that are associated with altered mitochondrial function.