BIMS Modules
BIMS students have the flexibility to choose from over 40, six-weeks, modular courses focused on a wide array of topics in biomedical sciences. In these higher-level courses, our expectation is that the students will apply the tools that they have learned in the core course to synthesize and integrate the most current knowledge in the field.
BIMS Modules - Fall 1
Following is a description of courses offered during the Fall 1 module. Below there is a list of each course, to find out more about that course, click on that courses tab. Please see SIS for current information on days/times for class meetings.
Note: Some courses may include two modules and span the entire semester.
Instructor(s)
Zimring
Credits: 2
Prerequisites
None
Description
This course focuses on critical thinking skills in biology. Data generation, data interpretation, hypothesis testing, sources of error, logic constructs, and biases and confounders (and how to avoid them) will each be covered in depth. Applications to research, manuscript writing, peer-review, scientific presentations, and thesis defense will each be explored. Students will learn to better evaluate both their own science and that of others.
Previously Offered:
Fall 2022
Instructor(s)
Luckey
Credits: 2
Prerequisites
None
Description
A series of joint lectures by basic and clinical scientists that focuses on the clinical context of a specific biomedical problem and the contemporary research that has resulted in major advances and treatment of the disease. Note: Students may take part II before part I of this course.
Previously Offered:
Fall 2022
Instructor(s)
Jones, Martin
Credits: 2
Prerequisites
None.
Description
Students will learn the basic concepts, technology, and processes that guide the practical use of common statistical methods. The course introduces descriptive and inferential statistics and applications to real-world data. Students will reinforce learning with problem sets, a publicly sharable R portfolio, and a final project to achieve practical competence in the use of statistical software and interpretation of results.
Previously Offered:
Fall 2022
Instructor(s)
Manichaikul
Credits: 2
Prerequisites
None
Description
This course will cover fundamental topics in statistical genetics with a focus on concepts and methods critical to a concrete understanding of the application of statistical genetics to public health genomics. Major topics covered in this course include modes of genetic inheritance, heritability analysis, linkage and association mapping, integrative analysis leveraging molecular ‘omics’ data, and genetic risk prediction modeling.
Previously Offered:
Fall 2022
Instructor(s)
Zimmer
Credits: 2
Prerequisites
BIMS 6000 and BIOP 8201 or 8301
Description
This course is an advanced course targeted to Biophysics or Physiology graduate students providing a detailed introduction into macromolecular X-ray crystallography and cryo-electron microscopy. The course will be taught in two sections, (1) focus on X-ray crystallography and (2) on cryo-EM.
Previously Offered:
Fall 2022
Instructor(s)
Bushweller
Credits: 2
Prerequisites
BIOP 8201 and BIOP 8301
Description
Exploration of magnetic resonance spectroscopy as it is applied to biopolymers. The first module will cover principles of nuclear magnetic resonance (NMR) will be covered, including basic principles, homonuclear and heteronuclear NMR methods.
Previously Offered:
Fall 2022
Instructor(s)
Casanova
Credits: 2
Prerequisites
Instructor permission; identified research problem and substantial knowledge of background literature
Description
The ability to effectively communicate scientific concepts and justify proposed experiments are essential skills for biomedical researchers. The goals of this course are for trainees to learn and practice effective scientific proposal writing. The course will provide students with extensive peer and faculty mentoring in a workshop format as they each prepare an NIH NRSA-style fellowship application.
Previously Offered:
Fall 2022
Instructor(s)
Rutkowski
Credits: 2
Prerequisites:
MICR 8200 and MICR 8202 or instructor permission.
Description
The module will cover in depth selected contemporary topics in molecular and cellular immunology. Sessions are discussion-based and facilitated by faculty. Students will learn how to critically evaluate primary literature and to clearly present scientific information. Prerequisite: MICR 8200: Building Blocks of the Immune System and MICR 8202: Integration and Diversification of the Immune System or instructor permission.
Previously Offered:
Fall 2022
Instructor(s)
Criss
Credits: 2
Prerequisites
BIMS 6000 Core Course, MICR 8400, and Instructor Permission.
Description
The class provides a comprehensive study of pathogenic microbes and their unique and conserved mechanisms of virulence.
Previously Offered:
Fall 2022
Instructor(s)
Cliffe
Credits: 2
Prerequisites
MICR 8400 or Instructor Permission
Description
This year’s focus will be the current topics on virus-host cell interactions.
This module will cover recent topics from papers published in the past 12 months. Sessions will be based on published primary literature and will consist of discussions facilitated by the faculty with student participation heavily encouraged. Students will learn how to critically evaluate the primary literature and to clearly present scientific information. Topics will be focused primarily on host detection and defense mechanisms, and how viruses overcome these mechanisms to promote replication.
Session will consist of two journal articles/session. Each student enrolled in the course will present. Students are also required to write a short summary of the papers and discussion, which will be due prior to the following class
Previously Offered:
Fall 2022
Instructor(s)
Zimring
Credits: 2
Prerequisites
None
Description
This course focuses on critical thinking skills in biology. Data generation, data interpretation, hypothesis testing, sources of error, logic constructs, and biases and confounders (and how to avoid them) will each be covered in depth. Applications to research, manuscript writing, peer-review, scientific presentations, and thesis defense will each be explored. Students will learn to better evaluate both their own science and that of others.
Previously Offered:
Fall 2022
Instructor(s)
Luckey
Credits: 2
Prerequisites
None
Description
A series of joint lectures by basic and clinical scientists that focuses on the clinical context of a specific biomedical problem and the contemporary research that has resulted in major advances and treatment of the disease. Note: Students may take part II before part I of this course.
Previously Offered:
Fall 2022
Instructor(s)
Bullock
Credits: 2
Prerequisites
MICR 8200, MICR 8203, and MICR 8040
Description
This module will allow students to gain comprehensive understanding of the extensive interactions between the immune system and neoplasia. The course will focus on discussion of contemporary literature, and will require students to have a strong knowledge of innate and adaptive immunity.
Previously Offered:
Fall 2021
Instructor(s)
Creutz
Credits: 2
Prerequisites
PHY 8040 and 8041 recommended
Description
The course will cover the major classes of therapeutically relevant drugs, and how they work at the molecular and cellular levels. The major topics include: general principles, chemical mediators, drugs affecting major organ systems and chemotherapy of infectious and malignant disease.
Previously Offered:
Fall 2022
Instructor(s)
Harris
Credits: 2
Prerequisites
BIMS 6000
Description
This course will help students learn to effectively communicate scientific concepts and proposals in the field of Pharmacology. Trainees will practice effective science writing and will participate in extensive peer and faculty workshop sessions as they prepare materials for their Advancement to Candidacy Exam or for an NIH NRSA-style fellowship application.
Previously Offered:
Fall 2022
BIMS Modules - Fall 2
Following is a description of courses offered during the Fall 2 module. Below there is a list of each course, to find out more about that course, click on that courses tab. Please see SIS for current information on days/times for class meetings.
Note: Some courses may include two modules and span the entire semester.
Instructor(s)
Zimring
Credits: 2
Prerequisites
None
Description
This course focuses on critical thinking skills in biology. Data generation, data interpretation, hypothesis testing, sources of error, logic constructs, and biases and confounders (and how to avoid them) will each be covered in depth. Applications to research, manuscript writing, peer-review, scientific presentations, and thesis defense will each be explored. Students will learn to better evaluate both their own science and that of others.
Previously Offered:
Fall 2022
Instructor(s)
Luckey
Credits: 2
Prerequisites
None
Description
A series of joint lectures by basic and clinical scientists that focuses on the clinical context of a specific biomedical problem and the contemporary research that has resulted in major advances and treatment of the disease. Note: Students may take part II before part I of this course.
Previously Offered:
Fall 2022
Instructor(s)
Jones, Martin
Credits: 2
Prerequisites
BIMS 8380 or concurrent enrollment
Description
The course will expand students’ statistical programming skills to utilize disparate datasets to generate conclusions about complex questions. Students will reinforce learning with problem sets and assignments to achieve competence in the use of statistical software to clean and organize data and apply the correct statistical approach (ANOVA, Chi-Square, regression, multiple regression) to interpret results.
Previously Offered:
Fall 2022
Instructor(s)
Manichaikul
Credits: 2
Prerequisites
None
Description
This course will cover fundamental topics in statistical genetics with a focus on concepts and methods critical to a concrete understanding of the application of statistical genetics to public health genomics. Major topics covered in this course include modes of genetic inheritance, heritability analysis, linkage and association mapping, integrative analysis leveraging molecular ‘omics’ data, and genetic risk prediction modeling.
Previously Offered:
Fall 2022
Instructor(s)
Bushweller
Credits: 2
Prerequisites
BIOP 8030
Description
Exploration of magnetic resonance spectroscopy as it is applied to biopolymers. Data collection for structure determination, residual dipolar couplings, approaches to large systems, and the use of NMR to deduce information about the dynamic behavior of proteins will be covered. Finally, principles of electron paramagnetic resonance spectroscopy will be presented.
Previously Offered:
Fall 2022
Instructor(s)
Kenworthy, Levental
Credits: 2
Prerequisites
BIMS 6000
Description
This course will cover fundamental topics in statistical genetics with a focus on concepts and methods critical to a concrete understanding of the application of statistical genetics to public health genomics. Major topics covered in this course include modes of genetic inheritance, heritability analysis, linkage and association mapping, integrative analysis leveraging molecular ‘omics’ data, and genetic risk prediction modeling.
Previously Offered:
Fall 2022
Instructor(s)
Sutherland
Credits: 2
Prerequisites
BIMS 6000
Description
The course provides an introduction to Developmental Biology for graduate students entering with little or no prior coursework in Developmental Biology. The course will include both lectures and readings from the primary literature, with an emphasis on the experimental basis for our current understanding of developmental processes at the tissue, cellular, and molecular levels.
Previously Offered:
Fall 2022
Instructor(s)
Casanova
Credits: 2
Prerequisites
Instructor permission; identified research problem and substantial knowledge of background literature
Description
The ability to effectively communicate scientific concepts and justify proposed experiments are essential skills for biomedical researchers. The goals of this course are for trainees to learn and practice effective scientific proposal writing. The course will provide students with extensive peer and faculty mentoring in a workshop format as they each prepare an NIH NRSA-style fellowship application.
Previously Offered:
Fall 2022
Instructor(s)
Purow, Gioeli
Credits: 2
Prerequisites
MICR 8040 and MICR 8044
Description
This course will cover contemporary topics relevant to the detection and treatment of solid tumors and hematopoietic cancers. These include, but are not limited to, clinical trials, metabolism and cancer, cancer stem cells, cancer biomarkers, systems and networks in cancer. Students will attend organ-based tumor boards, which expose the students to the team-based approach for individualizing treatments that is practiced in the UVA Cancer Center. Prerequisite: Fundamentals in Cancer Biology
Previously Offered:
Fall 2022
Instructor(s)
Rutkowski
Credits: 2
Prerequisites
MICR 8200 and MICR 8202 or instructor permission.
Description
The module will cover in depth selected contemporary topics in molecular and cellular immunology. Sessions are discussion-based and facilitated by faculty. Students will learn how to critically evaluate primary literature and to clearly present scientific information. Prerequisite: MICR 8200: Building Blocks of the Immune System and MICR 8202: Integration and Diversification of the Immune System or instructor permission.
Previously Offered:
Fall 2022
Instructor(s)
Derre
Credits: 2
Prerequisites
MICR 8401 or MICR 8410
Description
This course will discuss the grant process including applications for federal and foundation grants, proposal writing and submissions, and grant reviews. A research proposal (based loosely on guidelines for NIH postdoctoral fellowship grant application) on a selected topic in Microbial Pathogenesis will be developed by each student (or student teams).
Previously Offered:
Fall 2022
Instructor(s)
Cliffe
Credits: 2
Prerequisites
Instructor Permission
Description
This year’s focus will be the current topics on virus-host cell interactions
This module will cover recent topics from papers published in the past 12 months. Sessions will be based on published primary literature and will consist of discussions facilitated by the faculty with student participation heavily encouraged. Students will learn how to critically evaluate the primary literature and to clearly present scientific information. Topics will be focused primarily on host detection and defense mechanisms, and how viruses overcome these mechanisms to promote replication.
Session will consist of two journal articles/session. Each student enrolled in the course will present. Students are also required to write a short summary of the papers and discussion, which will be due prior to the following class.
Previously Offered:
Fall 2022
Instructor(s)
Harris
Credits: 2
Prerequisites
None
Description
This course will explore how reciprocal crosstalk between the central nervous system (CNS) and the immune system contributes to health and disease. Attention will be paid to highlight how immune responses contribute to neurological disorders such as multiple sclerosis, stroke, Alzheimers disease, depression, anxiety, and autism.
Previously Offered:
Fall 2022
Instructor(s)
Zimring
Credits: 2
Prerequisites
None
Description
This course focuses on critical thinking skills in biology. Data generation, data interpretation, hypothesis testing, sources of error, logic constructs, and biases and confounders (and how to avoid them) will each be covered in depth. Applications to research, manuscript writing, peer-review, scientific presentations, and thesis defense will each be explored. Students will learn to better evaluate both their own science and that of others.
Previously Offered:
Fall 2022
Instructor(s)
Luckey
Credits: 2
Prerequisites
None
Description
A series of joint lectures by basic and clinical scientists that focuses on the clinical context of a specific biomedical problem and the contemporary research that has resulted in major advances and treatment of the disease. Note: Students may take part II before part I of this course.
Previously Offered:
Fall 2022
Instructor(s)
Borish
Credits: 2
Prerequisites
Prerequisite: MICR 8200 and MICR 8202
Description
This course will review clinical conditions caused by aberrant performance of the immune system, including their clinical presentations and consequences. Students will appreciate the pathological and immune dysfunction responsible for each disease and important areas of contemporary immune research that address critical components of each disease’s pathogenesis. Students will propose, delineate, and critique a focused research plan.
Previously Offered:
Fall 2020
Instructor(s)
Creutz
Credits: 2
Prerequisites
PHAR 9100 or instructor permission; PHY 8040 & 8041 recommended
Description
The course will cover the major classes of therapeutically relevant drugs, and how they work at the molecular and cellular levels. The major topics include: general principles, chemical mediators, drugs affecting the central nervous system.
Previously Offered:
Fall 2022
Instructor(s)
Harris
Credits: 2
Prerequisites
BIMS 6000
Description
This course will help students learn to effectively communicate scientific concepts and proposals in the field of Pharmacology. Trainees will practice effective science writing and will participate in extensive peer and faculty workshop sessions as they prepare materials for their Advancement to Candidacy Exam or for an NIH NRSA-style fellowship application.
Previously Offered:
Fall 2022
BIMS Modules - Spring 1
Following is a description of courses offered during the Spring 1 module. Below there is a list of each course, to find out more about that course, click on that courses tab. Please see SIS for current information on days/times for class meetings.
Note: Some courses may include two modules and span the entire semester.
Instructor(s)
Eby
Credits: 1
Prerequisites:
None
Description:
Beginning in 1989, the National Institutes of Health introduced a requirement that institutions provide a program of instruction in the responsible conduct of research (NIH Guide for Grants and Contracts, Volume 18, Number 45, 1989). This was later expanded to require that all fellows on NIH training grants should receive instruction in the responsible conduct of research. The requirement does not specify a particular format or curriculum. However, recommendations are made that several areas should be covered in the instruction: conflict of interest, responsible authorship, policies for handling misconduct, policies regarding the use of human and animal subjects, and data management. This course is designed to help student consider each of these areas and therein formulate an understanding of responsible conduct in research.
Previously Offered:
Spring 2022
Instructor(s)
Farber
Credits: 1
Prerequisites:
None
Description:
Each week, a UVA faculty member or guest lecturer will summarize current work in their area of research. The emphasis in these lectures will be on high-throughput genomic and bio-informatic approaches to elucidating the mechanisms of pathogenesis in human disease and disease models.
Previously Offered:
Spring 2022
Instructor(s)
Farber
Credits: 3
Prerequisites:
BIOL 3010 or BIOL 4210 or instructor consent
Description:
The course will cover human genetics and genomics, including the human/mammalian genome variation, determination of genomic variation on phenotype and disease risk, mapping and characterizing genetic variants on phenotype, determining the putative impact of genetic variants on gene expression (transcriptomics, epigenomics), the promise and implications of genome science on precision medicine and the ethical, legal & social implications.
(Crosslisted with PHS 5705 and BIOC 5705)
Previously Offered:
Spring 2021
Instructor(s)
Luckey
Credits: 2
Prerequisites:
None
Description:
This is a series of joint lectures by basic and clinical scientists that focuses on the clinical context of a specific biomedical problem and the contemporary research that has resulted in major advances and treatment of the disease. Note: Students may take part II before part I of this course. This is a series of joint lectures by basic and clinical scientists that focuses on the clinical context of a specific biomedical problem and the contemporary research that has resulted in major advances and treatment of the disease.
Previously Offered:
Spring 2022
Instructor(s)
Jones, Martin
Credits: 2
Prerequisites:
None
Description:
Students will learn the basic concepts, technology, and processes that guide the practical use of common statistical methods. The course introduces descriptive and inferential statistics and applications to real-world data. Students will reinforce learning with problem sets, a publicly sharable R portfolio, and a final project to achieve practical competence in the use of statistical software and interpretation of results.
Previously Offered:
Spring 2022
Instructor(s)
Lynch
Credits: 2
Prerequisites:
None
Description:
The Translational Science Course is designed to prepare graduate students to engage in cutting-edge basic science discovery; understand proof-of-concept research and industrial designed experiments; innovate and invent; create valuable intellectual properties; optimize patent enablements and claims; interact with regulatory agencies; champion entrepreneurship and commercialization activities; and enhance societal impact of basic research.
Previously Offered:
Spring 2022
Instructor(s)
Bekiranov, Ratan, Sheffield, Zang
Credits: 3
Prerequisites:
Instructor permission required
Description:
Students will learn foundational computational methods for analysis of data from genome, epigenome, and transcriptome sequencing experiments. The course will cover various biological data types, algorithms, statistical and computational methods, and application areas in genomics and systems biology. Prior coursework/experience in linear algebra, UNIX, and R and Python programming required.
Previously Offered:
Spring 2022
Instructor(s)
Farber
Credits: 3
Prerequisites:
BIOL 3010 or BIOL 4210 or instructor consent
Description:
The course will cover human genetics and genomics, including the human/mammalian genome variation, determination of genomic variation on phenotype and disease risk, mapping and characterizing genetic variants on phenotype, determining the putative impact of genetic variants on gene expression (transcriptomics, epigenomics), the promise and implications of genome science on precision medicine and the ethical, legal & social implications.
(Crosslisted with PHS 5705 and BIOC 5705)
Previously Offered:
Spring 2021
Instructor(s)
Smith
Credits: 2
Prerequisites:
None
Description:
The Chromatin course modules are designed to provide students with an in-depth understanding of chromatin structure and function. In Chromatin I, the focus will be on chromatin structure and organization, nucleosome and chromatin remodeling factors, and the multiple histone modifying enzymes that regulate DNA-templated cellular functions such as transcription, DNA replication, and repair.
Previously Offered:
Spring 2022
Instructor(s)
Redemann
Credits: 2
Prerequisites:
BIMS 6000
Description:
This course will introduce students to some of the physical and chemical underpinnings of molecular biophysics. Physical principles will be discussed and related to how they govern biological systems and how they enable important biophysical techniques. Topics: Equilibrium thermodynamics: mean behavior of ensembles at equilibrium, and Biological fluctuations: deviations from the mean.
Previously Offered:
Spring 2022
Instructor(s)
Dudley
Credits: 2
Prerequisites:
BIMS 6000 or instructor permission
Description:
This course examines the molecular basis of cancer and how environmental and hereditary factors cooperate to elicit the transformed phenotype and promote cancer progression. It is team taught by both basic scientists and clinical faculty, providing students with an introduction to clinical presentation, progression, and outcomes; genetic/cellular/tissue drivers of oncogenesis and metastasis; and therapeutic challenges for the treatment of cancer.
Previously Offered:
Spring 2022
Instructor(s)
Elliott
Credits: 2
Prerequisites:
Previous immunology class or instructor permission
Description:
This module will cover the different components of the adaptive and innate arms of the immune system with a focus on development and molecular pathways regulating these processes.
Previously Offered:
Spring 2022
Instructor(s)
Elliott
Credits: 1
Prerequisites:
None
Description:
The course will cover the science and policies governing the study of select agents, and emerging infectious diseases. Topics will include, but are not limited to pathogen characteristics, regulatory requirements, recognition and detection of intentional and natural outbreaks, emergency preparedness and interfaces with public health.
Previously Offered:
Spring 2022
Instructor(s)
Shin
Credits: 6
Prerequisites:
None
Description:
This advanced course introduces critical areas in neuroscience. In 3 sections, it covers: Molecular, Cellular, & Dev Neuroscience, Systems & Circuits, & Behavior & Disease. Will explore: nervous sys development, basic principles of neurobio, membrane & action potential, ion channels, synaptic transmission & modulation, brain structures, sensory & motor circuits, neurological disease, animal models used to study them & the clinical context.
Previously Offered:
Spring 2022
Instructor(s)
Luckey
Credits: 2
Prerequisites:
None
Description:
This is a series of joint lectures by basic and clinical scientists that focuses on the clinical context of a specific biomedical problem and the contemporary research that has resulted in major advances and treatment of the disease. Note: Students may take part II before part I of this course. This is a series of joint lectures by basic and clinical scientists that focuses on the clinical context of a specific biomedical problem and the contemporary research that has resulted in major advances and treatment of the disease.
Previously Offered:
Spring 2022
Instructor(s)
Owens
Credits: 2
Prerequisites:
None
Description:
The course will integrate background cellular and molecular knowledge into organ systems and whole animal, function. It is intended to provide the ability to integrate knowledge at the molecular level into function, the foundation of translational-based research. The physiology to be covered will include the nervous system, metabolism and endocrine systems.
Previously Offered:
Spring 2022
Instructor(s)
Isakson
Credits:2
Prerequisites:
PHY 8040
Description:
The class covers the broad range of vascular biology from the basic science to clinical implications. The class integrates new methods in the field and relationships to heart function.
Previously Offered:
Spring 2022
BIMS Modules - Spring 2
Following is a description of courses offered during the Spring 2 module. Below there is a list of each course, to find out more about that course, click on that courses tab. Please see SIS for current information on days/times for class meetings.
Note: Some courses may include two modules and span the entire semester.
Credits: 1
Prerequisites:
None
Description:
Beginning in 1989, the National Institutes of Health introduced a requirement that institutions provide a program of instruction in the responsible conduct of research (NIH Guide for Grants and Contracts, Volume 18, Number 45, 1989). This was later expanded to require that all fellows on NIH training grants should receive instruction in the responsible conduct of research. The requirement does not specify a particular format or curriculum. However, recommendations are made that several areas should be covered in the instruction: conflict of interest, responsible authorship, policies for handling misconduct, policies regarding the use of human and animal subjects, and data management. This course is designed to help student consider each of these areas and therein formulate an understanding of responsible conduct in research.
Credits: 2
Prerequisite:
BIOP 8020, Macromolecular Crystallography I
The course offers in depth coverage of theory and practical applications of X-ray diffraction methods to crystals of biological macromolecules and their complexes. Topics of the second module will cover phase determination, electron density interpretation, refinement, and model validation. Case studies will be presented by the students.
Credits:
Prerequisites:
None
Description:
Each week, a UVA faculty member or guest lecturer will summarize current work in their area of research. The emphasis in these lectures will be on high-throughput genomic and bio-informatic approaches to elucidating the mechanisms of pathogenesis in human disease and disease models.
Credits: 3
Prerequisites:
BIOL 3010 or BIOL 4210 or instructor consent
Description:
The course will cover human genetics and genomics, including the human/mammalian genome variation, determination of genomic variation on phenotype and disease risk, mapping and characterizing genetic variants on phenotype, determining the putative impact of genetic variants on gene expression (transcriptomics, epigenomics), the promise and implications of genome science on precision medicine and the ethical, legal & social implications.
(Crosslisted with PHS 5705 and BIOC 5705)
Credits: 2
Prerequisites:
None
Description:
This course introduces methods, tools, and software for reproducibly managing, manipulating, analyzing, and visualizing large-scale biomedical data. Specifically, the course introduces the R statistical computing environment and packages for manipulating and visualizing high-dimensional data, covers strategies for reproducible research, and culminates with analysis of data from a real RNA-seq experiment using R and Bioconductor packages.
Credits: 2
Prerequisites:
BIMS 6000 (CCIB)
Description: This course will introduce students to major techniques in molecular biophysics, such as X-ray crystallography, NMR, electron microscopy, mass spectrometry and fluorescence methods. The primary literature will be the main source of reading. During the course the instructors will introducing a different topic at each session and will discuss relevant papers and applications together with the students.
Credits: 2
Prerequisites:
BIMS 6000 (CCIB)
Description:
This module will cover topics not discussed in the Core Course and provide depth to topics covered in less detail. These will include, but are not limited to membrane biogenesis and trafficking, cytoskeleton dynamics and regulation, cell adhesion and motility, cell polarity, cell cycle control and regulation. The course will be primarily literature-based and emphasis will be placed on model systems, experimental design and data interpretation.
Credits: 2
Prerequisites:
MICR 8040
Description:
This course is a follow-up to Fundamentals in Cancer Biology. It examines hormonal regulation and signal transduction pathways in breast cancer and leukemia/lymphoma. Clinical and basic science faculty again team up to provide students with a comprehensive view of clinical aspects (early detection, diagnosis, epidemiology, prognosis, treatment, and prevention) and experimental strategies that reveal basic mechanisms underlying these diseases.
Credits: 2
Prerequisites:
MICR 8200, Building Blocks of the Immune System and Instructor Permission
Description:
This module will cover how the diverse components of the immune system are integrated and how this integration influences further maturation and differentiation of elements of the immune system under physiological and patho-physiological conditions. This will include responses to different types of pathogens.
Credits: 2
Prerequisites:
BIMS 6000 (CCIB)
Description:
This foundational module will cover fundamentals of the biology of bacteria and viruses. Bacteriology topics to be discussed include bacterial physiology, genetics, and gene regulation, and how these and other features impact drug discovery and pathogenesis. Virology topics to be discussed include virus structure and assembly, viral replication, viral genetic regulation, virus/immune interactions, and applications of viruses in 21st century.
Credits: 2
Prerequisites:
None
Description:
This course will provide the strong foundation in signal transduction in developing neurons. Upon completion of this course, students will understand signal transduction in neural development and beyond. This will be a combination of lecture and discussion of classic and contemporary literature.
Credits: 2
Prerequisites:
None
Description:
We will highlight mechanisms that allow the nervous system to produce complex behaviors. Using a bottom-up approach beginning with classical descriptions of ion channels & the mathematical models used to understand their gating properties. We describe how neurons communicate via chemical and electrical synapses. Finally, we describe how the specific connections among neurons enable structures in the brain to carry out complex tasks.
Credits: 2
Prerequisites:
None
Description:
This is a series of joint lectures by basic and clinical scientists that focuses on the clinical context of a specific biomedical problem and the contemporary research that has resulted in major advances and treatment of the disease. Note: Students may take part II before part I of this course. This is a series of joint lectures by basic and clinical scientists that focuses on the clinical context of a specific biomedical problem and the contemporary research that has resulted in major advances and treatment of the disease
Credits: 2
Prerequisites:
PHY 8040 or permission of instructor
Description:
The course will integrate background cellular and molecular knowledge into organ systems and whole animal, function. It is intended to provide the ability to integrate knowledge at the molecular level into function the foundation of translational-based research. Specifically, the physiology to be covered will include the heart, vasculature, kidney, GI, and muscle.
Credits: 2
Prerequisites:
PHY 8040 and PHY 8052
Description:
The class covers the broad range of vascular biology from the basic sciences to the clinical implications. In addition, the class integrates new methods in the field and relationships to heart function.