2008-2009 CGR
2008-2009
Cardiovascular Medicine Grand Rounds
Sept. 2, 2008
No CGR
Holiday
Top
Sept. 9, 2008
“VT Ablation:
Indications and New Technologies”
Srijoy Mahapatra, MD
Assistant Professor
University of Virginia
Charlottesville, VA
Biosketch
Learning Objectives: Following the lecture, participants should be able to:
identify whom to ablate
discover ways to bring your new ideas to the attention of tool developers
Top
Sept. 15, 2008
Note: MONDAY
“Multi-Modality Imaging in CAD”
Jeroen J. Bax, MD, PhD
Leiden University Medical Center
Cardiovascular Division
The Netherlands
Biosketch
Learning Objectives: Following the lecture, participants should be able to:
differentiate the techniques of anatomical imaging vs functional imaging
discuss the relative merits of these imaging techniques in the detection of coronary artery disease
Top
Sept. 23, 2008
“Protection from Reperfusion Injury by A2A
Adenosine Receptors on NKT and NK Cells”
Joel Linden, PhD
Professor of Medicine and
Vice Chair of Research
University of Virginia
Charlottesville, VA
Biosketch
Learning Objectives: Following the lecture, participants should be able to:
discuss how the immune system contributes to ischemia-reperfusion injury and MI
describe the evidence that inflammation contributes to heart failure.
Top
Sept. 30, 2008
“New Drugs for Atrial Fibrillation”
John P. DiMarco, MD, PhD
Professor of Medicine
Director CCEP Clinic
University of Virginia
Charlottesville, VA
Biosketch
Learning Objectives: Following the lecture, participants should be able to:
identify drugs for treatment of atrial fibrillation that are under development or regulatory review
discuss the potential value of new amiodarone analogs in antiarrhythmic therapy
Top
Oct. 7, 2008
7th Annual
Richard Savington Crampton Lectureship
“Pathological Cardiac Remodeling:
Mechanisms and Therapies”
Joseph A. Hill, MD, PhD
Professor of Medicine and Molecular Biology
James T. Willerson M.D. Distinguished
Chair in Cardiovascular Diseases
Frank M. Ryburn, Jr. Chair in Heart Research
Chief, Division of Cardiology
UT Southwestern Medical Center
Dallas, TX
Biosketch
Learning Objectives: Following the lecture, participants should be able to:
recognize fundamental aspects of the pathophysiology of load-induced heart failure and strategies to slow, arrest or reverse disease progression
identify the role of autophagy in the cardiomyocyte response to stress
identify the role of HDACs and FoxO as potential targets of novel therapy
Oct. 14, 2008
“New Frontiers in Heart Failure”
James D. Bergin, MD
Professor of Medicine
University of Virginia
Charlottesville, VA
Biosketch
Learning Objectives: Following the lecture, participants should be able to:
identify the usual treatment for heart failure with preserved systolic function.
discuss the impact of the cardiorenal syndrome on morbidity and mortality.
Top
Oct. 21, 2008
“An Evidence-Based Approach to
Optimizing Stroke Care”
David Chiu, M.D.
The Neurological Institute
The Methodist Hospital
Houston, Texas
Biosketch
Learning Objectives: Following the lecture, participants should be able to:
identify, evaluate and treat ischemic stroke
apply evidence-based long term strategies and therapies to prevent future vascular evenings in patients after discharge
Top
Oct. 28, 2008
“Advances in the Nonivasive Detection
of Myocardial Ischemia”
George A. Beller, MD
Professor of Medicine
University of Virginia
Charlottesville, VA
Biosketch
Learning Objectives: Following the lecture, participants should be able to:
identify advances in the noninvasive assessment of perfusion and metabolic abnormaties consequent to myocardial ischemia at stress and rest using SPECT and PET nuclear cardiology techniques
evaluate the ability of such noninvasive methodologies to better risk stratify patients with suspected or known CAD.
discuss the merits of a functional approach versus an anatomic approach to risk assessment in symptomatic and asymptomatic cohorts
Top
Nov 4, 2008
“Acute Management of STEMI:
Decision Making in the Emergency Department”
Stanley Rockson, M.D.
Chief of Consultative Cardiology
Stanford University
Palo Alto, California
Biosketch
Learning Objectives: Following the lecture, participants should be able to:
identify methods for improving time to reperfusion for patients diagnosed with STEMI
describe the updated ACC/AHA guidelines for the acute management of STEMI
discuss guidelines-based continuum of care that bridges acute management with long term secondary prevention post discharge
Top
Nov. 11, 2008
No CGR:
AHA Meeting Nov 8-12
New Orleans
Top
Nov. 18, 2008
“Therapeutic Angiogenesis:
Where We Are and Where We Are Going ”
Brian H. Annex, MD
George A. Beller, M.D. Lantheus Medical Imaging Distinguished Professor of Cardiovascular Medicine
Chief of the Cardiovascular Division
University of Virginia
Charlottesville, VA
Biosketch
Learning Objectives: Following the lecture, participants should be able to:
identify the definition of angiogenesis and how it applies to peripheral arterial disease
discuss the latest clinical trials
identify a potential future for this field
Top
Nov. 25, 2008
Holiday – No CGR
Dec. 2, 2008
“Contemporary Management of
Non-ST Elevation Acute Coronary Syndromes”
Lewis Lipson, MD
Associate Professor of Medicine
Cardiovascular Division
University of Virginia
Biosketch
Learning Objectives: Following the lecture, participants should be able to:
identify the evidence for Guideline recommendations for treatment of NSTEMI/UA.
describe use of intervention and anticoagulants in treatment of NSTEMI/UA.
Top
Dec. 9, 2008
“Sarcoidosis”
C. Edward Rose, M.D.
Pulmonary Division
University of Virginia
Biosketch
Learning Objectives: Following the lecture, participants should be able to:
identify the myriad of presentations of sarcoidosis and its diagnosis
evaluate when to treat and how to treat sarcoidosis, including cardiac sarcoidosis
Top
Dec. 16, 2008
“Chemokines and Neovascularization in
Coronary Artery Disease”
Ellen Keeley, M.D.
Associate Professor of Medicine
Interventional Cardiology
University of Virginia
Biosketch
Learning Objectives: Following the lecture, participants should be able to:
identify the pathophysiology of myocardial neovascularization and collateral formation
describe the mechanism through which chemokines serve as important mediators in neovascularization in many disease processes
Top
Dec. 23, 2008
Holiday
No CGR
Top
Dec. 30, 2009
Holiday
No CGR
Top
Jan 6, 2009
“Sleep Apnea”
Paul Suratt, M.D.
John L. Guerrant Professor of Internal Medicine
Pulmonary Division
University of Virginia
Biosketch
Learning Objectives: Following the lecture, participants should be able to:
describe the relationship between sleep apnea and cardiovascular disease
describe the relationship between sleep apnea and pulmonary hypertension
Top
Jan. 13, 2009
“Changing Paradigms in the Treatment of
Aortic Dissections: Are We Making Progress?”
John Kern, M.D.
Associate Professor of Surgery
University of Virginia
Biosketch
Learning Objectives: Following the lecture, participants should be able to:
discuss updates on new therapies for aortic dissections
describe how the management of aortic dissections has changed
identify the present day outcomes for patients with dissections
Top
Jan. 20, 2009
No CGR
Inauguration of
President-elect Barack Obama
Top
Jan. 27, 2009
“Diagnosis of and Treatment Strategies
for Mesenteric Ischemia”
Alan H. Matsumoto, M.D.
Professor and Interim Chair of Radiology
University of Virginia
Biosketch
Learning Objectives: Following the lecture, participants should be able to:
identify the significant difference in mortality between acute and chronic mesenteric ischemia;
describe an algorithm for the diagnostic evaluation of mesenteric ischemia
discuss the role of endovascular therapy in the management of both acute and chronic mesenteric ischemia
Top
Feb. 3, 2009
Women’s Heart Month
“Heart Disease in Women”
or
“Henry Higgins laments: Why can’t
a woman be more like a man?”
Dearing W. Johns, M.D.
Associate Professor
Cardiovascular Medicine
University of Virginia
Biosketch
Learning Objectives: Following the lecture, participants should be able to:
identify 3 ways coronary disease differs in women(presentation, pathophysiology, or detection)
describe 3 CHD risk factors with a higher impact in women
discuss the relative effectiveness of primary and secondary prevention measures in women vs men
Top
Feb. 10, 2009
Women’s Heart Month
“Heart Disease in Pregnancy”
Christian Chisholm, M.D.
Associate Professor
OB-GYN Maternal Fetal Medicine
University of Virginia
Biosketch
Learning Objectives: Following this case-based presentation, participants should be able to:
identify how cardiovascular adaptations to pregnancy may exacerbate underlying heart disease
develop a framework for counseling women with heart disease about pregnancy risks
Top
Feb. 17, 2009
Women’s Heart Month
“Acute Coronary Syndromes and Cardiovascular Mortality in Women: Do we need a new paradigm?”
Angela M. Taylor, M.D.
Assistant Professor
Cardiovascular Medicine
Co-Director Diabetes Cardiovascular Center
University of Virginia
Biosketch
Learning Objectives: Following the lecture, participants should be able to:
describe the pathophysiology of acute coronary syndromes and mortality in premenopausal women
describe the pathophysiology of acute coronary syndromes and mortality in postmenopausal women
identify the contribution of the metabolic syndrome and diabetes to mortality in women
Top
Feb. 24, 2009
Women’s Heart Month
“Gender Differences
in Vascular Disease”
Nancy Harthun, M.D.
Associate Professor
Thoracic and Cardiovascular Surgery
University of Virginia
Biosketch
Learning Objectives: Following the lecture, participants should be able to:
Top
Mar. 3, 2009
Special Event
Co-sponsored by
the Cardiovascular Research Center,
the Center for Public Health Genomics,
and the Cardiovascular Division
“Genetic Predictors of Vascular Disease”
Gail P. Jarvik, M.D., Ph.D.
Head, Division of Medical Genetics
Arno G. Motulsky Professor of Medicine
Joint Professor of Medicine and Genome Sciences
Adjunct Professor Epidemiology
Division of Medical Genetics
University of Washington
Seattle, WA
Note: This talk will take place in MR5
Room 1041
Biosketch
Top
Mar. 10, 2009
“Pitfalls in the Diagnosis and
Treatment of Pulmonary Hypertension”
Ivan M. Robbins, M.D.
Director, Adult Pulmonary Hypertension Center
Director, Flolan Program
Vanderbilt University Medical Center
Nashville, TN
Biosketch
Learning Objectives: Following the lecture, participants should be able to:
describe the appropriate evaluation of a patient with pulmonary hypertension
identify which patients should and should not receive PAH-specific therapy
Top
Mar. 17, 2009
“The Molecular Basis of
Inherited Arrhythmia Syndrome”
Barry London, M.D., Ph.D.
Director, UPMC Cardiovascular Institute
Chief, Division of Medicine
Professor of Medicine, Cell Biology & Physiology
University of Pittsburgh
Pittsburgh, PA
Biosketch
Learning Objectives: Following the lecture, participants should be able to:
identify the different gene mutations that cause sudden death and the mechanisms by which they predispose to arrhythmias
describe the work up for inherited sudden death and the role of genetic testing
discuss the process of identifying new arrhythmia genes and the potential applicability to common forms of sudden death
Top
Mar. 24, 2009
“Novel Transcatheter Approaches to
Aortic and Mitral Valve Disease”
D. Scott Lim, M.D.
Assoc Prof of Pediatrics and Medicine
Co-Director, Congenital Heart Program
University of Virginia
Biosketch
Learning Objectives: Following the lecture, participants should be able to:
discuss the available results from the recently completed EVEREST I and II Trials regarding percutaneous mitral valve repair
discuss the transcatheter aortic valve replacement trial, PARTNER
Top
Mar. 31, 2009
NO CGR
ACC Conference
Orlando Mar 28-31
Top
Apr. 7, 2009
“”Epigenomic Studies of Atherosclerosis”
Jessica Connelly, Ph.D.
Assistant Professor of Internal Medicine
Cardiovascular Division
University of Virginia
Biosketch
Learning Objectives: Following the lecture, participants should be able to:
identify epigenomic approaches currently used for the study of complex disease and determine applicability to your disease of interest
describe how deciding the epigenetic landscape of a specific cell type can guide disease gene discovery and identify functional polymorphisms
Top
Apr. 14, 2009
“A Team Approach to Managing Hyperglycemia
in ACS: Blueprint for Success”
Michelle F. Magee, MBBCh, M.D.
Director, MedStar Diabetes Institute and
MedStar Clinical Research Center
Washington Hospital Center
Georgetown University
Washington, DC
Biosketch
Learning Objectives: Following the lecture, participants should be able to:
evaluate the need to rapidly identify and utilize therapeutic interventions to treat hyperglycemia in the hospital setting
discuss new clinical data on the benefits of intensive insulin therapy in ACS patients and translate these data into clinical practice
define standards for hospital insulin protocols for glycemic control to enhance patient car
Top April 21, 2009
“Prediabetes, Diabetes, and Cardiovascular
Disease: Can We Do More?”
Richard W. Nesto, M.D.
Associate Clinical Professor of Medicine
Harvard Medical School
Medicine-Beth Israel-Deaconess
Chair of Cardiovascular Medicine
Lahey Clinic Medical Center
Burlington, MA
Biosketch
Learning Objectives: Following the lecture, participants should be able to:
identify the CV risks associated with prediabetes and Type 2 diabetes
describe the mechanisms responsible for residual risk for CVD beyond modification of CV risk factors
discuss current clinical trials evaluating drugs to control glycemia and their potential to reduce CV risk
Top
April 28, 2009
“COURAGE to Embrace a New Management
Paradigm of Optimal Medical Therapy in Patients
with Stable Coronary Artery Disease”
William E. Boden, M.D.
Clinical Chief
Division of Cardiovascular Medicine
Buffalo General Hospital
University of Buffalo
Buffalo, NY
Biosketch
Learning Objectives: Following the lecture, participants should be able to:
describe the anatomic and physiologic basis for developing myocardial ischemia in chronic stable CAD compared to acute coronary syndromes
identify the basis for treating obstructive coronary lesions and the role of pharmacologic and revascularization approaches in patients with stable CAD
discuss the results of the COURAGE trial and the therapeutic implications in clinical practice
Top
May 5, 2009
Grollman Lecture
John P. Cooke, M.D., Ph.D.
Professor of Medicine – Cardiovascular Medicine
Associate Director (Education and Training)
Stanford Cardiovascular Institute
Stanford University
Stanford, CA
Biosketch
Medical Grand Rounds
8:00 – 9:00 a.m.
Jordan Hall Auditorium
“Myths, Misperceptions and Missed
Opportunities in the Management of PAD”
Learning Objectives: Following the lecture, participants should be able to:
begin diagnosing peripheral arterial disease on an office examination
employ non-invasive diagnostic studies in the diagnosis of PAD
treat PAD and the associated medical conditions
Cardiology Grand Rounds
12:00 -1:00 p.m.
Camp Heart Auditorium
“Therapeutic Angiogenesis and
Vascular Regeneration: The
Promise of Induced Pluripotential Cells”
Learning Objectives: Following the lecture, participants should be able to:
discriminate amongst the various types of stem cells for cardiovascular regeneration
identify the methods to generate and characterize induced pluripotential cells
develop their own proposals regarding pre-clinical assessment and clinical investigations using induced pluripotential stem cells
Top
May 12, 2009
“Deciphering the Molecular and Signaling
Mechanisms of Catabolic Muscle Wasting”
Zhen Yan, Ph.D.
Associate Professor
Cardiovascular Research Center (CVRC)
University of Virginia
Charlottesville, VA
Biosketch
Learning Objectives: Following the lecture, participants should be able to:
link catabolic muscle wasting to both the proteasome- and lysosome-dependent proteolytic processes
describe the major cellular signaling pathways involved in catabolic muscle wasting
differentiate between oxidative and glycolytic myofibers in their susceptibilities to cachectic stimuli
Top
May 19, 2009
“The Adult with
Congenital Heart Disease”
Robert W. Battle, M.D.
Assoc Prof of Medicine and Pediatrics
Co-Director, Congenital Heart Program
University of Virginia
Biosketch
Learning Objectives: Following the lecture, participants should be able to:
describe the history of congenital heart disease and the current status of the growing population of these patients
identify downstream complications: pitfalls in diagnosis and treatment
discuss research advances
Top
May 26, 2009
“Emerging Technologies: The Future of
Percutaneous Coronary Intervention”
David Jones, M.D.
Graduating Interventional Fellow
University of Virginia
Biosketch
Learning Objectives: Following the lecture, participants should be able to:
identify the past and current problems/challenges in interventional cardiology
discuss the pathophysiology and vascular biology associated with these problems
identify areas of research and development currently under way including the sparse clinical trials data available
describe possible future directions in the field of interventional imaging and adjunctive therapy
Top
June 2, 2009
Acute Decompensated
Heart Failure
Freddie Williams, M.D.
Graduating Fellow
University of Virginia
Biosketch
Learning Objectives: Following the lecture, participants should be able to:
identify the clinical presentation of acute decompensated heart failure
discuss current and emerging therapeutic strategies for treatment of acute decompensated heart failure
Top
June 9, 2009
Percutaneous Coronary Intervention (PCI)
Decisions: Applying the Guidelines,
Individualizing Therapy
Spencer B. King, M.D.
Executive Director of Academic Affairs,
St Joseph’s Health System,
President of the St Joseph’s Heart and Vascular Institute Professor of Medicine Emeritus at Emory University
Atlanta, GA
Biosketch
Learning Objectives: Following the lecture, participants should be able to:
discuss a standardized approach to risk stratification of patients with NSTEMI based on current guidelines
describe and assess recent data on the safety and efficacy of drug-eluting stents and bare-metal stents
identify guideline recommendations for long term management of patients with STEMI and NSTEMI post-PCI
Top
June 16, 2009
“To Statin or to Nonstatin?
Considering Absolute Risk is the Answer”
Christopher M. Rembold, M.D.
Professor of Internal Medicine and Physiology
Director of EKG Lab
University of Virginia
Biosketch
Learning Objectives: Following the lecture, participants should be able to:
discuss the concept of absolute risk reduction
identify the relative and significant benefits of statins, fibrates, niacin, fish oil and the Mediterranean diet in the treatment of CAD
Top