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Right place, right time – Spatial guidance of neuronal morphogenesis by septin GTPases

Radler MR, Spiliotis ET. Right place, right time - Spatial guidance of neuronal morphogenesis by septin GTPases. Curr Opin Neurobiol. 2022 Aug;75:102557. doi: 10.1016/j.conb.2022.102557. Epub 2022 May 21. PMID: 35609489; PMCID: PMC9968515.

35609489

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MicroRNA-223 limits murine hemogenic endothelial cell specification and myelopoiesis

Wu Y, Paila U, Genet G, Hirschi KK. MicroRNA-223 limits murine hemogenic endothelial cell specification and myelopoiesis. Dev Cell. 2023 Jun 6:S1534-5807(23)00240-X. doi: 10.1016/j.devcel.2023.05.007. Epub ahead of print. PMID: 37295435.

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Mechanisms of skin vascular maturation and maintenance captured by longitudinal imaging of live mice

Kam CY, Singh ID, Gonzalez DG, Matte-Martone C, Solá P, Solanas G, Bonjoch J, Marsh E, Hirschi KK, Greco V. Mechanisms of skin vascular maturation and maintenance captured by longitudinal imaging of live mice. Cell. 2023 May 25;186(11):2345-2360.e16. doi: 10.1016/j.cell.2023.04.017. Epub 2023 May 10. PMID: 37167971; PMCID: PMC10225355.

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Connexin 37 sequestering of activated-ERK in the cytoplasm promotes p27-mediated endothelial cell cycle arrest

Acharya BR, Fang JS, Jeffery ED, Chavkin NW, Genet G, Vasavada H, Nelson EA, Sheynkman GM, Humphries MJ, Hirschi KK. Connexin 37 sequestering of activated-ERK in the cytoplasm promotes p27-mediated endothelial cell cycle arrest. Life Sci Alliance. 2023 May 17;6(8):e202201685. doi: 10.26508/lsa.202201685. PMID: 37197981; PMCID: PMC10192821.

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Rational engineering of lung alveolar epithelium

Leiby KL, Yuan Y, Ng R, Raredon MSB, Adams TS, Baevova P, Greaney AM, Hirschi KK, Campbell SG, Kaminski N, Herzog EL, Niklason LE. Rational engineering of lung alveolar epithelium. NPJ Regen Med. 2023 Apr 28;8(1):22. doi: 10.1038/s41536-023-00295-2. PMID: 37117221; PMCID: PMC10147714.

37117221

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Connexin 43-mediated neurovascular interactions regulate neurogenesis in the adult brain subventricular zone

Genet N, Genet G, Chavkin NW, Paila U, Fang JS, Vasavada HH, Goldberg JS, Acharya BR, Bhatt NS, Baker K, McDonnell SP, Huba M, Sankaranarayanan D, Ma GZM, Eichmann A, Thomas JL, Ffrench-Constant C, Hirschi KK. Connexin 43-mediated neurovascular interactions regulate neurogenesis in the adult brain subventricular zone. Cell Rep. 2023 Apr 11;42(4):112371. doi: 10.1016/j.celrep.2023.112371. Epub ahead of print. PMID: 37043357.

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Transformation of alignment files improves performance of variant callers for long-read RNA sequencing data

de Souza VBC, Jordan BT, Tseng E, Nelson EA, Hirschi KK, Sheynkman G, Robinson MD. Transformation of alignment files improves performance of variant callers for long-read RNA sequencing data. Genome Biol 24, 91 (2023). https://doi.org/10.1186/s13059-023-02923-y

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Pyramidal neuron morphogenesis requires a septin network that stabilizes filopodia and suppresses lamellipodia during neurite initiation

Radler MR, Liu X, Peng M, Doyle B, Toyo-Oka K, Spiliotis ET. Pyramidal neuron morphogenesis requires a septin network that stabilizes filopodia and suppresses lamellipodia during neurite initiation. Curr Biol. 2023 Feb 6;33(3):434-448.e8. doi: 10.1016/j.cub.2022.11.043. Epub 2022 Dec 19. PMID: 36538929; PMCID: PMC9905282.

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Septins mediate a microtubule-actin crosstalk that enables actin growth on microtubules

Nakos K, Alam MNA, Radler MR, Kesisova IA, Yang C, Okletey J, Tomasso MR, Padrick SB, Svitkina TM, Spiliotis ET. Septins mediate a microtubule-actin crosstalk that enables actin growth on microtubules. Proc Natl Acad Sci U S A. 2022 Dec 13;119(50):e2202803119. doi: 10.1073/pnas.2202803119. Epub 2022 Dec 7. PMID: 36475946; PMCID: PMC9897426.

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