Oct 25 “Metabolic Stress Hormone FGF21: From Thirsty to Thin” by Steve Kliewer

October 25, 2018 by zrb8mf@virginia.edu

[PINN 1-17] Hosted by Irina Bochkis, Steven Kliewer, PhD, is a Professor and Diana K. and Richard C. Strauss Distinguished Chair in Developmental Biology in Molecular Biology and Pharmacology, UT Southwestern Medical Center, Dallas, TX

Dr. Kliewer runs a joint laboratory with Dr. David Mangelsdorf. Their research focuses on the roles of nuclear receptors and endocrine FGFs in regulating diverse aspects of physiology and pathophysiology, including metabolism and related diseases. Among their ongoing projects, they are studying how FGF19 and FGF21 regulate bile acid and energy homeostasis, respectively, and how the dafachronic acid receptor, DAF-12, regulates the infectious lifecycle of parasitic nematodes