Nov 09 “The Dynamic Epileptic Brain” by Christophe Bernard
11/9/2017
[Pinn Hall 1-17] Hosted by Mark Beenhakker, Christophe Bernard, PhD is Director of the Physiology & Physiopathology of Neuronal Networks Group(PhysioNet), Institut de Neurosciences des Systemes. After an initial training in theoretical physics and mathematics, he did a Ph.D. on "Theoretical and experimental analysis of cellular activity in the cerebellum". He then did a Post Doc in Southampton University with Howard Wheal on synaptic plasticity in an experimental model of Temporal Lobe Epilepsy. Since then, his activity has been focused on the mechanisms underlying the construction of an epileptic brain. He has been awarded with the Michael Prize in 2007. Focus of the Physiology & Physiopathology of Neuronal Networks Group (PhysioNet) that Dr. Bernard Leads: The principal objective is to understand how physiological and pathological behaviors emerge from the organization and the reorganization of the underlying neuronal architecture. The group's research is structured around five themes: 1. Cell/network dynamics and learning in physiological and pathological conditions (in epileptic patients, monkeys and rodents) 2. Mechanisms leading to the construction of an epileptic brain (in epileptic patients, monkeys and rodents) 3. Anatomo-functional organization of normal and epileptic networks (in epileptic patients, monkeys and rodents) 4.Coupling between metabolism, chloride homeostasis and cell/network function (in rodents) 5. (NEW) Neuroengineering: this research field is developed by a new group inside Physionet, lead by Dr. Adam Williamson, recipient of the ERC Starting Grant 2016 Six sub-groups explore different aspects of these themes: Human epilepsies (PI: F. Bartolomei) Dynamics of cells and networks (PI: C. Bernard) Structural and Neurochemical properties of neuronal networks (PI: M. Esclapez) Metabolism and Neuroprotection (PI: Y. Zilberter) Dynamics of chloride homeostasis (PI: P. Brest) Neuroengineering (PI: A. Williamson) Cognitive processes depend upon the activity of distributed networks in the brain. Our main goal is to further our understanding of the basic rules of neuronal activity in given behavioral states in physiological conditions, and how these rules are modified in epilepsy. Under this theme, we are trying to understand how different brain regions communicate to each other and exchange information, using multisite in vivo recordings in normal and epileptic animals. Brain trajectories are analyzed under various behavioral conditions. This work is done in close collaboration with the TNG team of V. Jirsa. One level down, we are trying to understand how neurons are connected to each other functionally in vivo, using silicon probe recordings in normal and epileptic animals. Our goal is to understand the dynamics of the connectivity maps between the temporal lobe and its connected areas.
Oct 26 “Mechanisms and Function of Polyploidy in the Liver” by Andrew Duncan
10/26/2017
[Pinn Hall 1-17] Hosted by Michelle Bland , Andrew W. Duncan, Phd, is an Assistant Professor of Pathology at the University of Pittsburg Research Interests: Research in the Duncan lab focuses on liver development, homeostasis and regeneration. Polyp...
Sep 14 Pharmacology Seminar by Jonathan Kagan
9/14/2017
[Pinn Hall 1-17] Hosted by Bimal Desai, Jonathan Kagan, Phd, is an Associate Professor of Pediatrics, Harvard Medical School Research Focus Area: Signal transduction pathways of the immune system Ancient signaling pathways lie at the base of the ini...
Sep 14 Pharmacology Seminar by Jonathan Kagan
9/14/2017
[Pinn Hall 1-17] Hosted by Bimal Desai, Jonathan Kagan, Phd, is an Associate Professor of Pediatrics, Harvard Medical School Research Focus Area: Signal transduction pathways of the immune system Ancient signaling pathways lie at the base of the ini...
Aug 31 Pharmacology Seminar by Sheila Collins
8/31/2017
[Pinn Hall 1-17] Hosted by Thurl Harris, Sheila Collins is a Professor of the Integrative Metabolism Program, Sanford Burnham Prebys Medical Discovery Institute. Dr. Collins's laboratory is interested in the biochemical mechanisms that regulate body ...
5/26/2017
[Mckim Hall, Sandridge Auditorium] Ms. Sarah Gray is a Pharmacology PhD Candidate in Eugene Barrett's Lab
5/26/2017
[Mckim Hall, Sandridge Auditorium] Ms. Sarah Gray is a Pharmacology PhD Candidate in Eugene Barrett's Lab
May 04 “Central Control of Peripheral Glucose Metabolism” Pharmacology Seminar by Sabrina Diano, PhD
5/4/2017
[Pinn Hall 1-17] Sabrina Diano, PhD, Principal Investigator, Professor of Obstetrics, Gynecology, and Reproductive Sciences, of Comparative Medicine and of Neuroscience, Director, Reproductive Neurosciences Group, Yale School of Medicine RESEARCH INT...
4/27/2017
[Pinn Hall 1-17] Hosted by Julius Zhu. Synaptic Structural Plasticity: From Molecules to Cognitive Functions and Disease. Research in my lab centers on signal transduction networks that regulate the structural and functional plasticity of excitatory...
4/19/2017
[Pinn 5023] Ms. Boroda is a Pharmacology PhD Candidate in Thurl Harris's lab.