6/17/2025
Research in our laboratory is now focused primarily on Alzheimer’s disease (AD), the most common form of a group of neurodegenerative disorders known collectively as tauopathies. The histopathological hallmark of…
6/17/2025
Research in the DeSimone laboratory centers on the problem of morphogenesis, which is the process biological systems use to generate form and develop increasingly complex structures needed to carry out…
6/17/2025
Biological processes ranging from gene transcription to behavior oscillate and are synchronized to the 24-hour day/night cycle. Mammalian circadian rhythms, orchestrated by the hypothalamic suprachiasmatic nucleus (SCN) allow appropriately timed…
6/17/2025
Why do some animals have the ability to regenerate certain tissues and organs, while others have lost this capacity? The study of regenerative biology and medicine have shown that the…
6/17/2025
WE USE FROGS TO STUDY DEVELOPMENT, DISEASE, AND REGENERATION PRECISION MEDICINE OF BIRTH DEFECTS Every parent that loses their baby to a birth defect wants to know why and if it will…
6/17/2025
The Pani lab pursues curiosity-driven research exploring the cell biological foundations of development and tissue maintenance. Cell-cell signaling performs critical functions in development, homeostasis, and disease. In normal conditions, cell signaling…