6/17/2025
Our research investigates the biology of the lipid mediator, sphingosine 1-phosphate (S1P). S1P concentration gradients are known to influence immune cell positioning. Indeed, S1P type 1 receptor agonist drugs are…
6/17/2025
My laboratory uses behavioral, pharmacological, and molecular techniques to delineate the neurobiological basis of addiction. We are particularly interested in determining the biological basis of sex differences in vulnerability to…
6/17/2025
Our research is in the field of human genetics. Specifically, we are studying the molecular genetics and biology of myotonic dystrophy (DM), the most common inherited neuromuscular disorder in adults.…
6/17/2025
The Meliza Lab is interested in understanding the extraordinary ability of sensory systems to learn complex patterns in a diverse and unstable world. We are particularly interested in how the…
6/17/2025
We are working to understand the over-all organization of the circadian systems of vertebrates. Currently we have focused our attention on a transgenic rat model in which one of the…
6/17/2025
CNS drug delivery, neuro-oncology, pituitary disorders, pituitary tumors, cerebral vasospasm
6/17/2025
The Patel lab focuses on understanding the cellular mechanisms by which seizures are initiated in SCN8A epileptic encephalopathy (DEE13). SCN8A EE is a severe genetic epilepsy syndrome caused by de…
6/17/2025
Current work in the lab is focused on developing gene therapies for pharmacoresistant epilepsies and insulin replacement. In these projects we are leveraging our experience in molecular cloning to develop…
6/17/2025
Light is critical for many biological processes. While vision is the most obvious of these, much of our "non-visual" physiology is regulated by light. For example, the internal 24-hour (circadian)…
6/17/2025
We explore the role of myeloid cell recruitment into the central nervous system after subarachnoid hemorrhage and to determine which effector molecules in neutrophils and monocytes are responsible for the…