6/17/2025
Analytical Neurochemistry I am interested in the development and characterization of analytical techniques to measure neurochemical changes. Measurements in the brain are challenging because zeptomole quantities of neuroactive molecules must be…
6/17/2025
Our research focus is to understand the structure and function of unusual DNA sequences in living cells, and how these sequences cause genome instability and lead to human diseases. Human…
6/17/2025
Many diseases of the nervous system (both neurodevelopmental and neurodegenerative) as well as degenerative and regenerative processes after injury can be traced at the cellular level to disruptions of endolysosomal…
6/17/2025
We are interested in studying how microbes evolve, adapt and diversify at the molecular, organismal and community levels. To gain insights into the fundamental mechanisms underlying these processes, we use…
6/17/2025
How gene expression is regulated in chromatin is a fundamental question in molecular biology. The transcription program is a major determinant of cell identity; transcriptional regulation is involved in many…
6/17/2025
Under certain conditions, all essential biopolymers, such as polypeptides, nucleic acids and polysaccharides, have to cross at least one membrane to reach their final destinations. Examples include the secretion of…
6/17/2025
To treat cancer effectively, great efforts have been devoted to molecularly targeted therapy. While there have been great examples of success, cancer cells often develop drug resistance to evade therapy.…
