6/17/2025
Ongoing work in my laboratory focuses on the role of an alternative splicing factor, the RNA helicase DDX39B, known to immunologists as BAT1, on immunity and autoimmunity. The connection to…
6/17/2025
The goal of my research is to understand the mechanistic underpinnings of the cell signaling network that contribute to cancer progression and resistance to therapy. My laboratory is currently focused…
6/17/2025
6/17/2025
My research is focused on elucidating the immunoregulatory mechanism by Hepatitis C virus (HCV). HCV is a global health concern causing severe liver disease such as fibrosis, cirrhosis and hepatocellular…
6/17/2025
Many mammalian and viral genes are alternatively spliced and subject to regulation at the post- transcriptional level. However, relatively little is known about the cellular mechanisms for this regulation. We…
6/17/2025
Maintaining tissue integrity is critical for a healthy body. Cell competition ensures tissue integrity by eliminating sick cells from the population. However, oncogenic mutations can convert a normal cell into…
6/17/2025
Introduction: Mitochondria are often pictured in biology texts as static, individual organelles, when in reality they form highly dynamic and mobile networks constantly undergoing fusion and fission. Research in the last…
6/17/2025
Supporting the research of faculty in the Microbiology, Immunology, and Cancer Biology department by analyzing high-throughput experimental data and helping investigators better understand their results.
6/17/2025
Pathogenesis of Kaposi's Sarcoma-Associated Herpesvirus Kaposi's sarcoma (KS) remains one of the two most common AIDS-associated malignancies and is caused by the human herpesvirus, KSHV, first discovered in 1994. Nevertheless,…
6/17/2025
Chemical and nutrient signaling are fundamental for all cellular processes, including interactions between the mammalian host and the microbiota, which have a significant impact on health and disease. My lab…
