Molecular Biosensors; Spatiotemporal Regulation of Biological Signaling; Protein Engineering for Imaging, Diagnostics, and Therapeutics
Novel Signaling Networks in the Regulation of Vascular Contractility: Role of the Sodium Calcium Exchanger (NCX1)
Drug Development Targeting Transcription Drivers in Cancer; Structure/Function Studies of Transcription Factor Drivers in Cancer
Molecular mechanisms responsible for the phenotypic transition of vascular cells, including smooth muscle cells (SMCs), endothelial cells (ECs) and macrophages during atherogenesis and vascular injury
Data management and analysis for scientific endeavors, particularly X-ray crystallography.
Our primary interest is in the mechanisms by which protein molecules accomplish their diverse biological tasks.