6/17/2025
Oligodendrocyte precursor cells (OPCs, or NG2 glia) comprise the largest pool of progenitor cells in the brain and continuously generate myelin-producing oligodendrocytes throughout our life until aging onset. However, how…
6/17/2025
Our laboratory is focused on understanding how immunological pathways contribute to neurodegenerative, neurodevelopmental, mental and behavior disorders. We are actively investigating the cellular and molecular pathways that contribute to neuroinflammation…
6/17/2025
Our team studies how neurons assemble into circuits and how those circuits adapt to the environment. We use state-of-the-art neuroscience tools in the rodent visual system to ultimately understand how learning…
10/6/2025
6/17/2025
Repair of the stereocilia actin core (project leader: Elizabeth Wagner) Hair bundles are complex structures that have to be maintained throughout the life of the organism, because mature mammalian hair cells…
6/17/2025
Glial cells support normal brain function by maintaining ion and neurotransmitter homeostasis, by regulating local blood flow and by stabilizing the blood brain barrier. Many diseases present with an impairment…
6/17/2025
Trophic interactions and factors are necessary for the survival and normal function of both synaptic partners in all systems, whether they are nerve-nerve or nerve-muscle. However, knowledge of the cellular…
6/17/2025
My laboratory is interested in understanding the pathogenetic mechanism of Huntington's disease (HD). HD is a dominantly inherited neurodegenerative disorder that affects about 1 in 10,000 people in the United…
