6/17/2025
Tyrosine phosphorylation is a protein modification that can occur during or after translation of a protein.The phosphate addition to a tyrosine residue, regulated by tyrosine kinases and phosphatases, can result…
6/17/2025
All the way up to the 20th century, the human genome has been optimized to survive in environments characterized by fluctuations between periods of feast and famine. These survivor-genomes clash…
6/17/2025
Systems analysis has become a requirement for making sense of high-throughput data and for characterizing properties of biological networks. In order to extend these recent developments to medical applications, there…
6/17/2025
The overarching goal of our research is functional understanding of molecular alterations in lung cancer. To that end, we determine impacts of genomic and transcriptomic alterations on tumor development and…
6/17/2025
My laboratory studies how nuclear transport and signal transduction control the compartmentalization and activity of transcription factors, particularly in the context of prostate cancer. A major focus of these studies…
6/17/2025
Director of Graduate Studies for Microbiology, Immunology and Cancer BiologyPlease contact Dr. Pemberton for any information or guidance regarding our graduate program. Associate Director of Education, UVA Comprehensive Cancer CenterDr…
6/17/2025
I am interested in mechanisms of bacterial pathogenesis. My research currently is focused on understanding the interactions of Clostridioides diffcile with intestinal cells and the associated impact on the immune…
6/17/2025
Our research on viruses provides insight not only into the diseases they cause, but it also leads to the discovery of novel basic mechanisms that operate in eukaryotic cells. Over…
6/17/2025
Understanding how gene expression is regulated in response to signals from both inside and outside the body plays a critical role in allowing us to adapt to changes in the…
6/17/2025
My graduate work investigated the link between adipose tissue inflammation and oxidative stress. Adipose tissue inflammation is an underlying cause of obesity-associated insulin resistance, affecting millions of people in the…
