6/17/2025
Chemical and nutrient signaling are fundamental for all cellular processes, including interactions between the mammalian host and the microbiota, which have a significant impact on health and disease. My lab…
6/17/2025
The long-term goal of our research program is to elucidate the roles of peripheral and central glia and glial-glial interactions during nervous system development, maintenance and disease/injury. Using Danio rerio…
6/17/2025
Bioinformatics Core: As a Bioinformatics Core Director at the University of Virginia, I have been privileged to work with great colleagues and have the opportunity to make contributions to biomedical…
6/17/2025
Targeted therapy: by serendipity, we identified a novel oncogene, and found that multiple cancers are addicted to its activity. This oncogene addiction is evidenced in glioblastoma, pediatric sarcoma, and others.…
6/17/2025
Dr. Loughran's current research includes: current research includes: • R01 grant from the NIH’s National Cancer Institute to identify and characterize the LGL leukemia virus and understand how it might cause leukemia; •…
6/17/2025
My research lies in the areas of statistical genetics and genetic epidemiology with an emphasis on 1) analysis of genome-wide association studies in the multi-ethnic cohort studies, 2) gene-based analysis…
6/17/2025
My laboratory's research focus involves the application of modern genomics and bioinformatics approaches to unravel complex and rare cardiovascular diseases. By integrating large-scale human genetic association and whole genome sequencing…
6/17/2025
Our laboratory studies macromolecular structures with an aim toward an in-depth understanding of structure-function relationships. X-ray diffraction analysis is our primary research tool, but we also employ other physical and…
6/17/2025
Tyrosine phosphorylation is a protein modification that can occur during or after translation of a protein.The phosphate addition to a tyrosine residue, regulated by tyrosine kinases and phosphatases, can result…
