6/17/2025
6/17/2025
Project Title: Pathogenesis of Infections by Herpes Simplex Virus Herpes simplex virus is widespread in the human population with most people exposed during childhood. Nearly all adults have specific antibodies. HSV-1…
6/17/2025
A main goal of research in the Brown Lab centers on the genetics of host resistance to viral infection, and the role of natural killer (NK) cells in viral immunity.…
6/17/2025
The focus of our work is on the use of costimulatory pathways, particularly the CD70-CD27 TNF-superfamily members, to promote immunotherapeutic T cell responses against melanoma and other malignancies, and as…
6/17/2025
Drug Development Targeting Transcription Drivers in Cancer Dysregulation of gene expression is a hallmark of all cancers. It is critical for self-renewal and chemo-resistance of cancer cells which contributes to…
6/17/2025
6/17/2025
Our group engineers biomaterials to better understand the dynamic interplay between cells and their microenvironment. We apply these platforms to address fundamental human health challenges including: - Treatment of fibrotic diseases -…
6/17/2025
Arf family GTPases and their function in membrane trafficking and cell motility Cell biology of bacterial infection The innate immune response to bacterial infection
6/17/2025
My research focuses on unravelling the complex genetic mechanisms underlying risk of colorectal cancer in order to enhance disease surveillance leading to improved health outcome. Our approach integrates large-scale human…
6/17/2025
The Chalfant Laboratory has historically focused on two major, but diverse areas of basic science in regard to Biochemistry, Biophysics, and Molecular Biology. Specifically, the Chalfant Laboratory studies mechanisms of…
