6/17/2025
The Ai lab specializes in protein engineering and employs interdisciplinary approaches, including biophysics, bioanalytical chemistry, chemical biology, synthetic biology, and optical imaging. One of our main areas of focus is the…
6/17/2025
Genetically engineering T cells with a chimeric antigen receptor (CAR) allows for recognition and subsequent destruction of cancer cells. While this has been a revolutionary treatment for many patients with…
6/17/2025
Mutations in any one of hundreds of genes cause neurodevelopmental disorders, like autism spectrum disorders and intellectual disability. For some unique genes, either an increase or decrease in their expression…
6/17/2025
My lab is primarily focused on both understanding and manipulating cell-ECM mechanotransduction pathways in homeostasis and disease. Our primary interest is in understanding how cells' changing microenvironment direct their phenotype…
6/17/2025
My laboratory is involved with developing Positron Emission Tomography (PET) and Magnetic Resonance Imaging (MRI) techniques as a tool for basic biomedical research. I am currently developing, fabricating, and testing…
6/17/2025
The general research program in this laboratory deals with how cells can exhibit directed movements of plasma membrane glycoproteins. In particular, we are studying the role of cytoskeleton-plasma membrane interactions…
6/17/2025
Research in our laboratory is now focused primarily on Alzheimer’s disease (AD), the most common form of a group of neurodegenerative disorders known collectively as tauopathies. The histopathological hallmark of…
6/17/2025
Arf family GTPases and their function in membrane trafficking and cell motility Cell biology of bacterial infection The innate immune response to bacterial infection
6/17/2025
My research focuses on unravelling the complex genetic mechanisms underlying risk of colorectal cancer in order to enhance disease surveillance leading to improved health outcome. Our approach integrates large-scale human…
6/17/2025
The longstanding interest of my laboratory is on the regulation of membrane trafficking in the secretory and endocytic pathways. A new direction that is a major focus of our research…
