6/17/2025
Systems analysis has become a requirement for making sense of high-throughput data and for characterizing properties of biological networks. In order to extend these recent developments to medical applications, there…
6/17/2025
The Important Role of the Microcirculation: Every organ in the body is dependent on blood flow to provide the necessary oxygen and nutrients in order to stay alive. The circulatory system…
6/17/2025
How do the regulatory networks that maintain gene expression programs change in response to stimuli and in disease states? The primary goal of my research program is to address this…
6/17/2025
1. Detection of genomic variation: I have developed several methods to identify and map variants (SNPs, indels, and large-scale rearrangements) from large-scale sequencing datasets. This includes identification and genotyping of…
6/17/2025
Cell signaling networks coordinate a wide variety of cellular physiology and gene regulatory programs. Perturbations in these signaling networks contribute to the pathogenesis of many diseases, including cardiovascular disease, cancer…
6/17/2025
My research is at the interface of computation and biology, drawing on techniques in computer science, data science, bioinformatics, and statistics, and applying them to biological questions in cancer, epigenetics,…
6/17/2025
The post-genomic era is marked by the development of technologies which have revealed the astonishing molecular diversity of gene products. Multiple distinct protein forms, or “proteoforms”, can arise through several…
6/17/2025
Agnieszka Swiatecka-Urban studied the regulation of cell-surface stability and intracellular trafficking of membrane proteins in epithelial cells. One focus of her research activity has been the characterization of mechanisms and…
6/17/2025
My laboratory studies the biological conflict between bacteria and the viruses that infect them: bacteriophages (phages). Bacteriophages are the most abundant entity on the planet, and are crucial for controlling…
6/17/2025
Research in my laboratory currently focuses on several very different aspects of plant cell growth and differentiation. One area of current interest is an examination of the biochemical, cellular, and…