6/17/2025
Mutations in any one of hundreds of genes cause neurodevelopmental disorders, like autism spectrum disorders and intellectual disability. For some unique genes, either an increase or decrease in their expression…
6/17/2025
My lab is primarily focused on both understanding and manipulating cell-ECM mechanotransduction pathways in homeostasis and disease. Our primary interest is in understanding how cells' changing microenvironment direct their phenotype…
6/17/2025
DNA replication-coupled repair, genome integrity networks, DNA damage tolerance pathways.
6/17/2025
6/17/2025
The Chalfant Laboratory has historically focused on two major, but diverse areas of basic science in regard to Biochemistry, Biophysics, and Molecular Biology. Specifically, the Chalfant Laboratory studies mechanisms of…
6/17/2025
What are the mechanisms by which neuronal and nonneuronal forms of structural plasticity contribute to social memory in the healthy and diseased brain? To answer this question, my lab uses…
6/17/2025
The Coutinho-Budd lab is interested in the cellular and molecular aspects of glial cell development and function. Glia are critical components of the nervous system—almost everything that neurons do requires…
6/17/2025
Background and Summary of Previous Findings: Neural development involves competition at many levels, whether it be axons innervating a target or synapses refining a connection. Over 50 years ago, Viktor…
6/17/2025
Research in the DeSimone laboratory centers on the problem of morphogenesis, which is the process biological systems use to generate form and develop increasingly complex structures needed to carry out…
6/17/2025
Development of the Cerebral Cortex Your cerebral cortex mediates your conscious sensory perceptions, thoughts, and behaviors. To perform these functions, the cortex must develop the proper structure and circuitry during…
