6/17/2025
The cardiovascular system is the first organ system to form in vertebrates and it is essential for embryonic survival. This system continually grows and remodels to meet the increasing energetic…
6/17/2025
My research primarily focuses on t the genetic/molecular epidemiology of cancer and the human microbiome. My past and current research have discovered novel genetic variants, polygenic risk scores, epigenetic biomarkers,…
6/17/2025
How gene expression is regulated in chromatin is a fundamental question in molecular biology. The transcription program is a major determinant of cell identity; transcriptional regulation is involved in many…
6/17/2025
Protein abundance and post-translational modifications (PTMs) are tightly regulated to control cellular activities and developmental processes. Dysregulated protein function, either through abnormal protein levels or PTMs, disrupts normal cellular activities…
6/17/2025
During the development of chronic lung disease, repetitive environmental insults/injuries, such as cigarette smoke, respiratory viruses infection and allergy lead to ineffective repair in the genetically susceptible subjects. Molecular understanding on…
6/17/2025
Alloimmunity in Transfusion and Transplantation , Oxidant Stress Biology in Health and Disease
6/17/2025
To treat cancer effectively, great efforts have been devoted to molecularly targeted therapy. While there have been great examples of success, cancer cells often develop drug resistance to evade therapy.…