6/17/2025
Our research on viruses provides insight not only into the diseases they cause, but it also leads to the discovery of novel basic mechanisms that operate in eukaryotic cells. Over…
6/17/2025
Humans are colonized with trillions of microorganisms, collectively termed the microbiota. Aside from providing a first line of defense to invading pathogens or aiding in digestion and metabolism, commensal microbes…
6/17/2025
The Spencer lab studies host-pathogen interactions of Gram-positive bacteria, focusing on the major neonatal pathobiont Group B Streptococcus (GBS). GBS can asymptomatically colonize the female genital tract, leading to transmission…
6/17/2025
The Sun Lab at the University of Virginia investigates how the immune system responds to viral infections, chronic conditions, and aging, with particular emphasis on long COVID, cancer and aging…
6/17/2025
My laboratory studies the biological conflict between bacteria and the viruses that infect them: bacteriophages (phages). Bacteriophages are the most abundant entity on the planet, and are crucial for controlling…
6/17/2025
Our lab studies the structure and function of several membrane proteins of clinical importance in their natural membrane environment. We are also interested in the roles that membrane lipids play…
6/17/2025
Human immunodeficiency viruses (HIV) crossed the species barrier from non-human primates multiple times in Central Africa leading to the establishment of two distinct HIV types (HIV-1 and HIV- 2) which…
6/17/2025
Papillomaviruses cause the most common lethal malignancy in women world-wide: cervical cancer. Our laboratory studies the actions of the papillomavirus E6 oncoprotein. By identifying host proteins that associate with E6,…
6/17/2025
Research in my lab focuses on advancing knowledge of how the human immune system responds to environmental triggers that worsen lung disease. The prevalence of asthma has risen dramatically in…
6/17/2025
We are interested in studying how microbes evolve, adapt and diversify at the molecular, organismal and community levels. To gain insights into the fundamental mechanisms underlying these processes, we use…