6/17/2025
The post-genomic era is marked by the development of technologies which have revealed the astonishing molecular diversity of gene products. Multiple distinct protein forms, or “proteoforms”, can arise through several…
6/17/2025
6/17/2025
An international expert on subjects related to hypertension, Dr. Siragy was the first to discover that stimulation of angiotensin AT2 receptor leads to generation of nitric oxide. Siragy has authored…
6/21/2025
Our research focuses on the molecular basis of smooth muscle contraction, the role of RhoA GTP exchange factors (GEFs) and GTP activating proteins (GAPs) in smooth muscle signaling, and identifying…
6/17/2025
The Sonkusare laboratory studies the role of ion channels and calcium signaling mechanisms in regulating vascular function and blood pressure. Constriction of small arteries is a crucial determinant of blood…
6/17/2025
6/17/2025
In eukaryotes, approximately 30% of all newly synthesized proteins pass through the endoplasmic reticulum (ER), where they undergo folding and maturation. A significant fraction of nascent proteins may fail to…
6/17/2025
Agnieszka Swiatecka-Urban studied the regulation of cell-surface stability and intracellular trafficking of membrane proteins in epithelial cells. One focus of her research activity has been the characterization of mechanisms and…
6/17/2025
Our lab studies the structure and function of several membrane proteins of clinical importance in their natural membrane environment. We are also interested in the roles that membrane lipids play…
6/17/2025
