6/17/2025
The Agaisse Lab is associated with the Department of Microbiology, Immunology, and Cancer Biology (MIC). Our laboratory studies the bacterial pathogen Shigella flexneri, which causes approximately 270 million cases of…
6/17/2025
6/17/2025
Signaling between cells in the brain relies on electrical and chemical transmission. Ion channels traverse brain cell membranes to serve as conduits for the flow of ionic current, which creates…
6/17/2025
Machine Learning/AI for Biomedical Applications: Development of innovative advanced machine learning approaches including knowledge-guided meta-learning explainable machine learning frameworks that take advantage of the relationships between genes, cell types, clinical variables,…
6/17/2025
6/17/2025
Drug Development Targeting Transcription Drivers in Cancer Dysregulation of gene expression is a hallmark of all cancers. It is critical for self-renewal and chemo-resistance of cancer cells which contributes to…
6/17/2025
Membranes and membrane proteins participate in some of the most important and interesting cellular processes. Energy transduction, cell signaling, membrane excitability, secretion and immune recognition are examples of a few…
6/17/2025
Membrane proteins facilitate the transfer of information across lipid bilayers, comprise approximately 25% of a typical proteome, and represent over half of all drug targets. The membrane proteins that mediate…
6/17/2025
Current funded projects in the laboratory: (1) Elucidation of molecular mechanisms controlling smooth muscle contractility; (2) Development of drugs against the influenza and Ebola viruses; (3) Studies of the mechanism of protein crystallization…
8/6/2025
The mission of Dr. Nikolay Dokholyan’s laboratory is to uncover the molecular etiology of neurodegenerative diseases. The lab focuses on understanding, detecting, and controlling proteins implicated in neurodegenerative diseases, such…
