6/17/2025
Current funded projects in the laboratory: (1) Elucidation of molecular mechanisms controlling smooth muscle contractility; (2) Development of drugs against the influenza and Ebola viruses; (3) Studies of the mechanism of protein crystallization…
6/17/2025
Drug Discovery and Molecular Biology of Pathogenic RNA viruses: Ebola, SARS-CoV-2, Influenza and Zika COVID-19, Influenza, Zika fever, and Ebola hemorrhagic fever are diseases caused by highly pathogenic RNA viruses that…
6/17/2025
Genetics of complex disease Common diseases, such as osteoporosis, impart significant societal health burdens. These diseases are, in part, regulated by genetic determinants and understanding their genetic basis is critical to…
6/17/2025
They have no symptoms, but subjects with untreated hypertension and salt sensitivity will have major health challenges such as blindness, stroke, kidney failure, and heart attacks. These devastating (and costly)…
6/17/2025
Our research focuses on the application of chemical engineering principles to problems in microbial ecology. The aim is to develop a fundamental understanding of mechanisms underlying microbial behavior which will…
6/17/2025
My laboratory, in collaboration with my colleague Dr. Jon Bjarnason, was one of the first to identify and characterize the metalloproteinases present in numerous snake venoms. These Snake Venom Metalloproteinases;…
6/17/2025
Our research program is concerned with the synthesis, properties and applications of metal complexes with polymeric ligands. These multifunctional targets are prepared by combining coordination chemistry with living polymerization methodologies.…
6/17/2025
There are two morphologically distinct forms of the HIV-1 virus, called immature and mature. The immature virion is the form that initially assembles and initiates budding from the plasma membrane.…
6/17/2025
One major focus of our work is to study the cellular and molecular consequences of the blood supply in the eye. Specifically, we are interested in quantifying the biomechanical changes…
6/17/2025
Dr. Guerlain conducts research in human-automation interaction, design of decision support systems, cognitive systems engineering, and intelligent tutoring as systems applied to complex systems, such as medical, petrochemical, and military…
