6/17/2025
A main goal of research in the Brown Lab centers on the genetics of host resistance to viral infection, and the role of natural killer (NK) cells in viral immunity.…
6/17/2025
6/17/2025
Arf family GTPases and their function in membrane trafficking and cell motility Cell biology of bacterial infection The innate immune response to bacterial infection
6/17/2025
Research description: Herpes simplex viruses type 1 and type 2 are significant human pathogens. Approximately 65% of the US population are infected with HSV-1 and 20% with HSV-2. The viruses persist…
6/17/2025
Membrane proteins facilitate the transfer of information across lipid bilayers, comprise approximately 25% of a typical proteome, and represent over half of all drug targets. The membrane proteins that mediate…
6/17/2025
6/17/2025
The Cowardin laboratory, located within the Child Health Research Center at the University of Virginia, focuses on understanding how the gut microbiota during pregnancy and early postnatal life set the…
6/17/2025
My current research includes investigations into the emergence and dissemination of antibiotic resistance among bacterial pathogens. Especially interesting are novel examinations regarding how modifications of lipid A that confer colistin…
6/17/2025
Our laboratory studies N. gonorrhoeae, an obligate human bacterial pathogen that causes the sexually transmitted infection gonorrhea. Gonorrhea has existed within the human population for all of recorded history and…
6/17/2025
We study the molecular mechanisms underlying the interaction between pathogens and their mammalian host. In particular, we investigate how the obligate intracellular bacteria Chlamydia trachomatis manipulates the host and establishes…