6/17/2025
Chemical and nutrient signaling are fundamental for all cellular processes, including interactions between the mammalian host and the microbiota, which have a significant impact on health and disease. My lab…
6/17/2025
A. Personal Statement I am an active, practicing vascular surgeon who has also maintained an independently funded basic science/translational research laboratory since 2003. My clinical practice is focused on the care…
6/17/2025
Human development, immunity, wound healing, fertility, and nutrient uptake all depend upon the ability of cells to change shape. Acquisition of an asymmetric or polarized morphology by a cell is…
6/17/2025
6/17/2025
Our research focuses on cancer with a special interest in glioblastoma, the most aggressive tumor type of the brain which to date is still considered a deadly disease. Our lab…
6/17/2025
Epigenetic changes accompany an individual’s development, aging, and disease. They’re particularly significant markers for cancer’s onset and progression, posing substantial therapeutic challenges. Increasing evidence suggests that DNA replication stress leads…
6/17/2025
Our laboratory is focused on understanding how immunological pathways contribute to neurodegenerative, neurodevelopmental, mental and behavior disorders. We are actively investigating the cellular and molecular pathways that contribute to neuroinflammation…
6/17/2025
Our research is in the field of human genetics. Specifically, we are studying the molecular genetics and biology of myotonic dystrophy (DM), the most common inherited neuromuscular disorder in adults.…
6/17/2025
The major focus of my lab is to understand how the genetic drivers of cancer fuel tumor evolution and to mechanistically define how these genes contribute to various tumor phenotypes.…
6/17/2025
Within cells there exists a fine balance between survival and death. One of the earliest steps in the development of cancer is the ability of a cell to escape death.…
