Mechanisms of Disc Degeneration and Back Pain
When intervertebral discs wear out, the annulus develops cracks and the nucleus can herniate out these crack, like the jelly squeezing out through a hole in the donut. Our bodies see the nucleus as a foreign body and attack it by sending cells to gobble it up. These cells release inflammatory chemicals that cause inflammation around the nerves, which can cause back/leg pain, numbness and/or weakness. In addition, the inflamed nerves make the muscles go into spasm. That is what causes the neck and low back pain.