Faculty
Herve Agaisse, Professor
Department of Microbiology, Immunology, and Cancer Biology
Genetic approaches, cellular and molecular biology of intracellular pathogen infection.
Huiwang Ai, Professor and Director of Center for Membrane and Cell Physiology
Department of Molecular Physiology and Biological Physics
Biosensors; Spatiotemporal Regulation of Biological Signaling; Protein Engineering for Imaging, Diagnostics, and Therapeutics
Huan Bao, Associate Professor
Department of Molecular Physiology and Biological Physics
Biophysics of membrane pore formation; research and therapeutic applications of lipid nanoparticles.
Douglas Bayliss, Joseph & Frances Larner Professor and Chair of Pharmacology
Department of Pharmacology
Mechanisms of neuromodulation in central neurons.
John H. Bushweller, Harrison Professor
Department of Molecular Physiology and Biological Physics
Drug Development Targeting Transcription Drivers in Cancer; Structure/Function Studies of Transcription Factor Drivers in Cancer
David S. Cafiso, Professor
Department of Chemistry
Molecular Mechanisms for Membrane Transport and Cell Signaling.
James E. Casanova, Professor
Department of Cell Biology
Role of Arf family GTPases in vesicular transport and cytoskeleton assembly. Cell biology of bacterial pathogenesis. Innate immune responses to bacterial infection.
Linda Columbus, Commonwealth Professor and Chair of Chemistry
Department of Chemistry
Biophysical Chemistry: Membrane protein structure, function, and dynamics.
Alison K. Criss, Harrison Professor
Department of Microbiology, Immunology, and Cancer Biology
Cellular and molecular mechanisms of Neisserial pathogenesis.
Bimal Desai, Professor
Department of Pharmacology
Ion channels and calcium signaling in inflammation, immunity and tissue homeostasis.
Douglas W. DeSimone, Ivy Pratt Professor and Chair of Cell Biology
Department of Cell Biology
Cell Adhesion and Adhesion-Dependent Cell Signaling in Vertebrate Morphogenesis.
Seham Ebrahim, Assistant Professor
Department of Molecular Physiology and Biological Physics
Cytoskeletal architecture, dynamics and roles in cellular physiology and disease; High-resolution live cell and tissue imaging.
Edward H. Egelman, Harrison Professor
Department of Biochemistry and Molecular Genetics
Structure and Function of Macromolecular Complexes Using Electron Microscopy.
Heather Ferris, Associate Professor
Department of Medicine: Endocrinology and Metabolism
Brain metabolism, cognitive decline, insulin signaling and Alzheimer’s disease
Sarah Flowers, Assistant Professor
Department of Neuroscience
Impact of APOE and lipid metabolism on cell function in Alzheimer’s disease.
Roseanne M. Ford, Professor
Department of Chemical Engineering
Bacterial attachment and biofilms, microbial transport in porous media.
Andreas Gahlmann, Associate Professor
Department of Chemistry
Super-resolution fluorescence imaging of bacterial cells.
Lu Gan, Associate Professor
Department of Molecular Physiology and Biological Physics
Chromosome organization in unicellular eukaryotes and Nucleosome rearrangement in chromosome condensation.
Karen Kemper Hirschi, Professor
Department of Cell Biology
Understanding Cellular and Molecular Mechanisms Leading to Blood Vessel Formation.
Brant Isakson, Professor
Department of Molecular Physiology and Biological Physics
Translating our discoveries in the microcirculation to tangible benefits in patients.
Lulu Jiang, Assistant Professor
Department of Neuroscience
Alzheimer’s Disease Pathogenesis; Tau Aggregation and Protein–Protein, Protein–Lipid, and Protein–RNA Interactions; Optogenetic and Human iPSC-Based 2D and 3D Models of Neurodegeneration
Ahmad Jomaa, Assistant Professor
Department of Molecular Physiology and Biological Physics
Localisation of nascent proteins to sub-cellular compartments.
David F. Kashatus, Associate Professor
Department of Microbiology, Immunology, and Cancer Biology
The Role of Mitochondrial Fusion and Fission in Tumorigenesis.
Anne Kenworthy, Professor
Department of Molecular Physiology and Biological Physics
Architecture and function of biological membranes.
Ilya Levental, Professor
Department of Molecular Physiology and Biological Physics
Composition, Biophysics and Physiology of Cellular Membranes.
Kevin R. Lynch, Professor
Department of Pharmacology
Chemical biology of sphingosine 1-phosphate.
Eyleen Jorgelina O’Rourke, Associate Professor
Department of Biology
Obesity and Aging.
Edward Perez-Reyes, Professor
Department of Pharmacology
Exploring epilepsy circuits then preventing seizures using gene therapies. Developing drug-inducible genetic switches for insulin replacement gene therapies.
Ling Qi, Andrew P. Somlyo Professor and Chair of MPBP
Department of Molecular Physiology and Biological Physics
Delineate the physiological importance and structure-function relationship of ER-associated degradation in humans.
Stefanie Redemann, Associate Professor
Department of Molecular Physiology and Biological Physics
Chromosome segregation and aneuploidy in meiosis and mitosis.
Jeffrey J. Saucerman, Professor
Department of Biomedical Engineering
Roles of complex signaling networks involved in the regulation of cardiovascular function and disease.
Natasha Sheybani, Assistant Professor and Research Director of FUSION Center
Department of Biomedical Engineering, UVA Focused Ultrasound Immuno-Oncology Center
Focused ultrasound bioeffects for immunomodulation and delivery; immune and gene therapies; multimodal molecular imaging; extracellular vesicle liquid biopsy.
Jung-Bum Shin, Associate Professor
Department of Neuroscience
Auditory Neurobiology
Karsten Siller, Associate Professor
School of Data Science
Image analysis, high-throughput data pipelines, and high-performance computing.
Swapnil Sonkusare, Professor
Department of Molecular Physiology and Biological Physics
Identify the calcium signaling abnormalities that lead to vascular dysfunction and blood pressure elevation in cardiovascular disorders.
Elias T. Spiliotis, Professor
Department of Cell Biology
Spatial Cell Biology. Neuronal Morphogenesis and Disease. Cancer Migration and Invasion.
Cliff Stains, Professor
Department of Chemistry
Chemical Biology Tools for Studying Cellular Communication; fluorescent and luminescent bioprobes; construction of designer signaling network.
Todd P. Stukenberg, Professor
Department of Biochemistry and Molecular Genetics
Mechanisms of chromosome segregation in Mitosis and generation of Chromosomal Instability in tumors.
Uday Tak, Assistant Professor
Department of Microbiology, Immunology, and Cancer Biology
Prokaryotic immune systems, bacteriophage virology, programmed cell death, pore-forming proteins, evolution of immunity, protein engineering
Lukas K. Tamm, Harrison Professor
Department of Molecular Physiology and Biological Physics
Biomembrane Structure and Function; Cell Entry of Enveloped Viruses; Neurosecretion by Exocytosis; Structure of Bacterial Pathogen Membrane Proteins; Lipid-Protein Interactions.
Ming-Feng Tsai, Associate Professor
Department of Molecular Physiology and Biological Physics
Molecular mechanisms and physiology of transporters and ion-channels, mitochondrial calcium transporters. Membrane biochemistry, electrophysiology, cryo-EM, and live-cell imaging.
Jarred M. Whitlock, Assistant Professor
Department of Molecular Physiology and Biological Physics
The formation, function, coordination, and pathology of multinucleated cell types that make up the placenta and musculoskeletal system.
Jie Yang, Assistant Professor
Department of Biochemistry and Molecular Genetics
Structural mechanisms of macromolecular complexes, Cryo-EM, Mitochondrial stress, Endoplasmic reticulum stress, Cellular stress response
Anny Xiaobo Zhou, E. Cato Drash Professor
Department of Medicine
Using genome-wide association studies (GWAS) to better understand lung biology and disease; functional genomics, lineage tracing mouse models, ex vivo organoid models and single live cell imaging
Jochen Zimmer, HHMI Investigator and Charles Slaughter Professor
Department of Molecular Physiology and Biological Physics
Transport of biopolymers across biological membranes with a particular interest in polysaccharide and protein translocation.
Hui Zong, Professor
Department of Microbiology, Immunology, and Cancer Biology
Early detection, cancer prevention, and tumor microenvironment.