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Faculty

Faculty

Herve AgaiseHerve Agaisse, Professor

Department of Microbiology, Immunology, and Cancer Biology
Genetic approaches, cellular and molecular biology of intracellular pathogen infection.


Huiwang AiHuiwang Ai, Professor

Department of Molecular Physiology and Biological Molecular
Biosensors; Spatiotemporal Regulation of Biological Signaling; Protein Engineering for Imaging, Diagnostics, and Therapeutics.


Huan BaoHuan Bao, Associate Professor

Department of Molecular Physiology and Biological Physics
Biophysics of membrane pore formation; research and therapeutic applications of lipid nanoparticles.


Doug BaylissDouglas Bayliss, Professor and Joseph and Frances Larner Chair

Department of Pharmacology
Mechanisms of neuromodulation in central neurons.


John H. Bushweller, Professor

Department of Molecular Physiology and Biological Physics
Drug Development Targeting Transcription Drivers in Cancer; Structure/Function Studies of Transcription Factor Drivers in Cancer


David CafisoDavid S. Cafiso, Professor

Department of Chemistry
Molecular Mechanisms for Membrane Transport and Cell Signaling.


James CasanovaJames E. Casanova, Professor

Department of Cell Biology
MRole of Arf family GTPases in vesicular transport and cytoskeleton assembly. Cell Biology of bacterial pathogenesis. The innate immune response to bacterial infection.


Linda ColumbusLinda Columbus, Professor

Department of Chemistry
Biophysical Chemistry: Membrane protein structure, function, and dynamics.


Alison CrissAlison K. Criss, Professor

Department of Microbiology, Immunology, and Cancer Biology
Cellular and molecular mechanisms of Neisserial pathogenesis.


Bimal DesaiBimal Desai, Professor

Department of Pharmacology
Ion channels and Ca2+-signaling in inflammation, immunity and tissue homeostasis.


Doug DeSimoneDouglas W. DeSimone, Ivy Pratt Professor of Morphogenesis and Chair

Department of Cell Biology
Cell Adhesion and Adhesion-Dependent Cell Signaling in Vertebrate Morphogenesis.


Seham EbrahimSeham Ebrahim, Assistant Professor

Department of Molecular Physiology and Biological Molecular
Cytoskeletal architecture, dynamics and roles in cellular physiology and disease; High-resolution live cell and tissue imaging.


Edward EgelmanEdward H. Egelman, Professor

Department of Biochemistry and Molecular Genetics
Structure and Function of Macromolecular Complexes Using Electron Microscopy.


Sarah FlowersSarah Flowers, Assistant Professor

Department of Neuroscience
Impact of APOE and lipid metabolism on cell function in Alzheimer’s disease.


Roseanne FordRoseanne M. Ford, Professor

Department of Chemical Engineering
Bacterial attachment and biofilms, microbial transport in porous media.


Andreas GahlmannAndreas Gahlmann, Associate Professor

Department of Chemistry
Super-resolution fluorescence imaging of bacterial cells.


Lu GanLu Gan, Associate Professor

Department of Molecular Physiology and Biological Physics
Chromosome organization in unicellular eukaryotes and Nucleosome rearrangement in chromosome condensation.


Karen HirschiKaren Kemper Hirschi, Professor

Department of Cell Biology
Understanding Cellular and Molecular Mechanisms Leading to Blood Vessel Formation.


Brant IsaksonBrant Isakson, Professor

Department of Molecular Physiology and Biological Physics
Translating our discoveries in the microcirculation to tangible benefits in patients.


Ahmad JomaaAhmad Jomaa, Assistant Professor

Department of Molecular Physiology and Biological Physics
Localisation of nascent proteins to sub-cellular compartments.


David KashatusDavid F. Kashatus, Associate Professor

Department of Microbiology, Immunology, and Cancer Biology
The Role of Mitochondrial Fusion and Fission in Tumorigenesis.


Anne KenworthyAnne Kenworthy, Professor

Department of Molecular Physiology and Biological Physics
Architecture and function of biological membranes.


Ilya LeventalIlya Levental, Professor

Department of Molecular Physiology and Biological Molecular
Composition, Biophysics and Physiology of Cellular Membranes.


Kevin LynchKevin R. Lynch, Professor and Vice Chair

Department of Pharmacology
Chemical biology of sphingosine 1-phosphate.


Eyleen O'RourkeEyleen Jorgelina O’Rourke, Associate Professor

Department of Biology
Obesity and Aging.


Edward Perez-ReyezEdward Perez-Reyes, Professor

Department of Pharmacology
Exploring epilepsy circuits then preventing seizures using gene therapies. Developing drug-inducible genetic switches for insulin replacement gene therapies.


Ling QiLing Qi, Andrew P. Somlyo Professor and Chair

Department of Molecular Physiology and Biological Physics
Delineate the physiological importance and structure-function relationship of ER-associated degradation in humans.


Stefanie RedemannStefanie Redemann, Associate Professor

Department of Molecular Physiology and Biological Physics
Chromosome segregation and aneuploidy in meiosis and mitosis.


Jeffrey SaucermanJeffrey J. Saucerman, Professor

Department of Biomedical Engineering
Roles of complex signaling networks involved in the regulation of cardiovascular function and disease.


Jung-Bum ShinJung-Bum Shin, Associate Professor

Department of Neuroscience
Auditory Neurobiology.


Swapnil SonkusareSwapnil Sonkusare, Associate Professor

Department of Molecular Physiology and Biological Physics
Identify the calcium signaling abnormalities that lead to vascular dysfunction and blood pressure elevation in cardiovascular disorders.


Avril SomlyoAvril V. Somlyo, Professor

Department of Molecular Physiology and Biological Physics
Novel signal transduction pathways in smooth muscles that regulate contractility and impact diseases of the vasculature, airway and gastrointestinal tract.


Elias SpiliotisElias T. Spiliotis, Professor

Department of Cell Biology
Spatial Cell Biology. Neuronal Morphogenesis and Disease. Cancer Migration and Invasion.


Todd StukenbergTodd P. Stukenberg, Professor

Department of Biochemistry and Molecular Genetics
Mechanisms of chromosome segregation in Mitosis and generation of Chromosomal Instability in tumors.


Uday Tak, Assistant Professor

Department of Microbiology, Immunology, and Cancer Biology
Prokaryotic immune systems, bacteriophage virology, programmed cell death, pore-forming proteins, evolution of immunity, protein engineering


Lukas TammLukas K. Tamm, Harrison Professor and Director of Center for Membrane and Cell Physiology

Department of Molecular Physiology and Biological Physics
Biomembrane Structure and Function; Cell Entry of Enveloped Viruses; Neurosecretion by  Exocytosis; Structure of Bacterial Pathogen Membrane Proteins; Lipid-Protein Interactions.


Ming-Feng TsaiMing-Feng Tsai, Associate Professor

Department of Molecular Physiology and Biological Physics
Our research focuses on molecular mechanisms and physiological functions of transporters and ion-channels, particularly Ca2+ transport proteins in mitochondria. We approach questions using a wide range of tools, including membrane-biochemistry, electrophysiology, cryo-electron microscopy, and live-cell imaging.


Jarred WhitlockJarred M. Whitlock, Assistant Professor

Department of Molecular Physiology and Biological Physics
The formation, function, coordination, and pathology of multinucleated cell types that make up the placenta and musculoskeletal system.


Jie YangJie Yang, Assistant Professor

Department of Biochemistry and Molecular Genetics
Structural mechanisms of macromolecular complexes, Cryo-EM, Mitochondrial stress, Endoplasmic reticulum stress, Cellular stress response


Jochen ZimmerJochen Zimmer, HHMI Investigator and Professor

Department of Molecular Physiology and Biological Physics
Transport of biopolymers across biological membranes with a particular interest in polysaccharide and protein translocation.


Hui ZongHui Zong, Professor

Department of Microbiology, Immunology, and Cancer Biology
Early detection, cancer prevention, and tumor microenvironment.