Faculty

Herve Agaisse

Agaisse, Hervé

Genetic approaches, cellular and molecular biology of intracellular pathogen infection

Associate Professor, Department of Microbiology, Immunology, and Cancer Biology

 

Huiwang Ai

Ai, Huiwang

Spatiotemporal Regulation of Biological Signaling; Protein Engineering for Imaging, Diagnostics, and Therapeutics

Associate Professor, Department of Molecular Physiology and Biological Physics

 

Paula Barrett

Barrett, Paula Q.

Regulation of low-voltage activated T-type Ca2+ channel activity by kinases and heterotrimeric G-proteins and their roles in physiological responses.

Professor, Department of Pharmacology

 

Douglas Bayliss

Bayliss, Douglas A.

Mechanisms of neuromodulation in central neurons

Professor and Joseph and Frances Larner Chair, Department of Pharmacology

 

John Bushweller

Bushweller, John H.

Drug Development Targeting Transcription Drivers in Cancer; Structure/Function Studies of Transcription Factor Drivers in Cancer; Structural Studies of Membrane Proteins

Professor, Department of Molecular Physiology and Biological Physics

 

David Cafiso

Cafiso, David S.

Molecular Mechanisms for Membrane Transport and Cell Signaling

Commonwealth Professor, Department of Chemistry

 

James Casanova

Casanova, James E.

Role of Arf family GTPases in vesicular transport and cytoskeleton assembly.
Cell Biology of bacterial pathogenesis.
The innate immune response to bacterial infection.

Professor, Department of Cell Biology

 

J. Castle

Castle, J. David

Intracellular cholesterol and the regulation of insulin secretion and membrane trafficking.

Professor, Department of Cell Biology

 

Linda Columbus

Columbus, Linda

Biophysical Chemistry: Membrane protein structure, function, and dynamics

Associate Professor, Department of Chemistry

 

Carl Creutz

Creutz, Carl E.

Calcium-dependent, membrane-binding proteins and mechanisms of exocytosis

Professor, Department of Pharmacology

 

Alison Criss

Criss, Alison K.

Cellular and molecular mechanisms of Neisserial pathogenesis

Associate Professor, Department of Microbiology, Immunology, and Cancer Biology

 

Bimal Desai

Desai, Bimal N.

Ion channels and Ca2+-signaling in inflammation, immunity and tissue homeostasis

Associate Professor, Department of Pharmacology

 

Douglas DeSimone

DeSimone, Douglas W.

Cell Adhesion and Adhesion-Dependent Cell Signaling in Vertebrate Morphogenesis

Professor and Chair, Department of Cell Biology

 

Edward Egelman

Egelman, Edward H.

Structure and Function of Macromolecular Complexes Using Electron Microscopy

Harrison Professor, Department of Biochemistry and Molecular Genetics

 

Roseanne Ford

Ford, Roseanne M.

Bacterial attachment and biofilms, microbial transport in porous media

Professor, Department of Chemical Engineering

 

Andreas Gahlmann

Gahlmann, Andreas

Super-resolution fluorescence imaging of bacterial cells

Assistant Professor, Department of Chemistry

 

Karen Hirschi

Hirschi, Karen Kemper

Understanding Cellular and Molecular Mechanisms Leading to Blood Vessel Formation

Professor, Department of Cell Biology

 

Brant Isakson

Isakson, Brant

Translating our discoveries in the microcirculation to tangible benefits in patients.

Professor, Department of Molecular Physiology and Biological Physics

 

David Kashatus

Kashatus, David F

The Role of Mitochondrial Fusion and Fission in Tumorigenesis.

Associate Professor, Microbiology, Immunology, and Cancer Biology

 

Peter Kasson

Kasson, Peter M.

Mechanisms of cell entry by influenza; Viral glycan recognition; drug resistance; molecular dynamics simulation; distributed computing.

Associate Professor, Department of Molecular Physiology and Biological Physics

 

Anne Kenworthy

Kenworthy, Anne

Architecture and function of biological membranes

Professor, Department of Molecular Physiology and Biological Physics

 

Kevin Lynch

Lynch, Kevin R.

Chemical biology of sphingosine 1-phosphate

Professor, Department of Pharmacology

 

Robert Nakamoto

Nakamoto, Robert K.

Structure-Function of Active Transporters

Professor, Department of Molecular Physiology and Biological Physics

 

Eyleen O'Rourke

O’Rourke, Eyleen Jorgelina

Obesity and Aging

Assistant Professor, Department of Biology

 

Edward Perez-Reyes

Perez-Reyes, Edward

Exploring epilepsy circuits then preventing seizures using AAV-based gene therapies.

Professor, Department of Pharmacology

 

Owen Pornillos

Pornillos, Owen

Structure and assembly of HIV Virus/host interactions; Structural biology of the innate immune system

Associate Professor, Department of Molecular Physiology and Biological Physics

 

Kodi Ravichandran

Ravichandran, Kodi S.

Apoptotic cell clearance mechanisms in health and disease

Harrison Professor and Chair, Department of Microbiology, Immunology, and Cancer Biology

 

Stefanie Redemann

Redemann, Stefanie

Chromosome segregation and aneuploidy in meiosis and mitosis

Assistant Professor, Department of Molecular Physiology and Biological Physics

 

Jeffrey Saucerman

Saucerman, Jeffrey J.

Roles of complex signaling networks involved in the regulation of cardiovascular function and disease

Associate Professor, Department of Biomedical Engineering

 

Swapnil Sonkusare

Sonkusare, Swapnil

Microcirculation, vascular ion channels, calcium signaling mechanisms, endothelial cells, hypertension

Assistant Professor, Department of Molecular Physiology and Biological Physics

 

Avril Somlyo

Somlyo, Avril V.

Novel signal transduction pathways in smooth muscles that regulate contractility and impact diseases of the vasculature, airway and gastrointestinal tract.

Professor, Department of Molecular Physiology and Biological Physics

 

P. Todd Stukenberg

Stukenberg, P. Todd

Mechanisms of chromosome segregation in Mitosis and generation of Chromosomal Instability in tumors

Professor, Biochemistry and Molecular Genetics

 

Lukas Tamm

Tamm, Lukas K.

Biomembrane Structure and Function; Cell Entry of Enveloped Viruses; Neurosecretion by Exocytosis; Structure of Bacterial Pathogen Membrane Proteins; Lipid-Protein Interactions

Andrew P. Somlyo Professor,  Center Director, and Chair of Department of Molecular Physiology and Biological Physics

 

Judith White

White, Judith M.

Virus Entry into Cells: Mechanisms and Development of Anti-Viral Therapeutics

Professor, Department of Cell Biology

 

Michael Wiener

Wiener, Michael C.

Structure/function of integral membrane proteins; structural biophysics; enzymology and virology of ZMPSTE24; sparse-constraint structure determination; technology development

Professor, Department of Molecular Physiology and Biological Physics

 

Mark Yeager

Yeager, Mark

Cardiac Gap Junction Membrane Channels / IntegrinsWater Channels / Rotavirus / Reovirus / Retrovirus

Harrison Distinguished Professor,  Department of Molecular Physiology and Biological Physics

 

Jochen Zimmer

Zimmer, Jochen

Transport of biopolymers across biological membranes with a particular interest in polysaccharide and protein translocation.

Professor, Department of Molecular Physiology and Biological Physics

 

Hui Zong

Zong, Hui

Early detection, cancer prevention, and tumor microenvironment

Associate Professor, Department of Microbiology, Immunology, and Cancer Biology