Faculty

Associate Professor, Department of Microbiology, Immunology, and Cancer Biology

Herve Agaisse

Agaisse, Hervé

Genetic approaches, cellular and molecular biology of intracellular pathogen infection

Associate Professor, Department of Molecular Physiology and Biological Physics

Huiwang Ai

Ai, Huiwang

Molecular Biosensors; Spatiotemporal Regulation of Biological Signaling; Protein Engineering for Imaging, Diagnostics, and Therapeutics

Professor, Department of Pharmacology

Paula Barrett

Barrett, Paula Q.

Regulation of low-voltage activated T-type Ca2+ channel activity by kinases and heterotrimeric G-proteins and their roles in physiological responses.

Professor and Joseph and Frances Larner Chair, Department of Pharmacology

Douglas Bayliss

Bayliss, Douglas A.

Mechanisms of neuromodulation in central neurons

Professor, Department of Molecular Physiology and Biological Physics

John Bushweller

Bushweller, John H.

Drug Development Targeting Transcription Drivers in Cancer; Structure/Function Studies of Transcription Factor Drivers in Cancer

Commonwealth Professor, Department of Chemistry

David Cafiso

Cafiso, David S.

Molecular Mechanisms for Membrane Transport and Cell Signaling

Professor, Department of Cell Biology

James Casanova

Casanova, James E.

Role of Arf family GTPases in vesicular transport and cytoskeleton assembly.
Cell Biology of bacterial pathogenesis.
The innate immune response to bacterial infection.

Professor, Department of Cell Biology

J. Castle

Castle, J. David

Intracellular cholesterol and the regulation of insulin secretion and membrane trafficking.

Associate Professor, Department of Chemistry

Linda Columbus

Columbus, Linda

Biophysical Chemistry: Membrane protein structure, function, and dynamics

Professor, Department of Pharmacology

Carl Creutz

Creutz, Carl E.

Calcium-dependent, membrane-binding proteins and mechanisms of exocytosis

Associate Professor, Department of Microbiology, Immunology, and Cancer Biology

Alison Criss

Criss, Alison K.

Cellular and molecular mechanisms of Neisserial pathogenesis

Associate Professor, Department of Pharmacology

Bimal Desai

Desai, Bimal N.

Ion channels and Ca2+-signaling in inflammation, immunity and tissue homeostasis

Professor and Chair, Department of Cell Biology

Douglas DeSimone

DeSimone, Douglas W.

Cell Adhesion and Adhesion-Dependent Cell Signaling in Vertebrate Morphogenesis

Assistant Professor, Department of Molecular Physiology and Biological Physics

Seham Ebrahim

Ebrahim, Seham

Cytoskeletal architecture, dynamics and roles in cellular physiology and disease; High-resolution live cell and tissue imaging

Harrison Professor, Department of Biochemistry and Molecular Genetics

Edward Egelman

Egelman, Edward H.

Structure and Function of Macromolecular Complexes Using Electron Microscopy

Professor, Department of Chemical Engineering

Roseanne Ford

Ford, Roseanne M.

Bacterial attachment and biofilms, microbial transport in porous media

Assistant Professor, Department of Chemistry

Andreas Gahlmann

Gahlmann, Andreas

Super-resolution fluorescence imaging of bacterial cells

Professor, Department of Cell Biology

Karen Hirschi

Hirschi, Karen Kemper

Understanding Cellular and Molecular Mechanisms Leading to Blood Vessel Formation

Professor, Department of Molecular Physiology and Biological Physics

Brant Isakson

Isakson, Brant

Translating our discoveries in the microcirculation to tangible benefits in patients.

Assistant Professor, Department of Molecular Physiology and Biological Physics

Ahmad Jomaa

Jomaa, Ahmad

Localisation of nascent proteins to sub-cellular compartments

Associate Professor, Microbiology, Immunology, and Cancer Biology

David Kashatus

Kashatus, David F

The Role of Mitochondrial Fusion and Fission in Tumorigenesis.

Associate Professor, Department of Molecular Physiology and Biological Physics

Peter Kasson

Kasson, Peter M.

Physical mechanisms of infectious disease; influenza infection; membrane fusion; antibiotic resistance; molecular dynamics simulation; machine learning.

Professor, Department of Molecular Physiology and Biological Physics

Anne Kenworthy

Kenworthy, Anne

Architecture and function of biological membranes

Associate Professor, Department of Molecular Physiology and Biological Physics

Ilya Levental

Levental, Ilya

Composition, Biophysics and Physiology of Cellular Membranes

Professor, Department of Pharmacology

Kevin Lynch

Lynch, Kevin R.

Chemical biology of sphingosine 1-phosphate

Professor, Department of Molecular Physiology and Biological Physics

Robert Nakamoto

Nakamoto, Robert K.

Structure-Function of Active Transporters

Assistant Professor, Department of Biology

Eyleen O'Rourke

O’Rourke, Eyleen Jorgelina

Obesity and Aging

Professor, Department of Pharmacology

Edward Perez-Reyes

Perez-Reyes, Edward

Exploring epilepsy circuits then preventing seizures using gene therapies. Developing drug-inducible genetic switches for insulin replacement gene therapies.

Associate Professor, Department of Molecular Physiology and Biological Physics

Owen Pornillos

Pornillos, Owen

Structure and assembly of HIV, virus/host interactions, structural biology of the innate immune system

Harrison Professor and Chair, Department of Microbiology, Immunology, and Cancer Biology

Assistant Professor, Department of Molecular Physiology and Biological Physics

Stefanie Redemann

Redemann, Stefanie

Chromosome segregation and aneuploidy in meiosis and mitosis

Associate Professor, Department of Biomedical Engineering

Jeffrey Saucerman

Saucerman, Jeffrey J.

Roles of complex signaling networks involved in the regulation of cardiovascular function and disease

Associate Professor, Department of Molecular Physiology and Biological Physics

Swapnil Sonkusare

Sonkusare, Swapnil

Identify the calcium signaling abnormalities that lead to vascular dysfunction and blood pressure elevation in cardiovascular disorders

Professor, Department of Molecular Physiology and Biological Physics

Avril Somlyo

Somlyo, Avril V.

Novel signal transduction pathways in smooth muscles that regulate contractility and impact diseases of the vasculature, airway and gastrointestinal tract.

Professor, Biochemistry and Molecular Genetics

P. Todd Stukenberg

Stukenberg, P. Todd

Mechanisms of chromosome segregation in Mitosis and generation of Chromosomal Instability in tumors

Andrew P. Somlyo Professor,  Center Director, and Chair of Department of Molecular Physiology and Biological Physics

Lukas Tamm

Tamm, Lukas K.

Biomembrane Structure and Function; Cell Entry of Enveloped Viruses; Neurosecretion by Exocytosis; Structure of Bacterial Pathogen Membrane Proteins; Lipid-Protein Interactions

Professor, Department of Cell Biology

Judith White

White, Judith M.

Cell Biology

Professor, Department of Molecular Physiology and Biological Physics

Jochen Zimmer

Zimmer, Jochen

Transport of biopolymers across biological membranes with a particular interest in polysaccharide and protein translocation.

Associate Professor, Department of Microbiology, Immunology, and Cancer Biology

Hui Zong

Zong, Hui

Early detection, cancer prevention, and tumor microenvironment