The Nephrology Clinical Research Center and IGNITE-KUH Clinical and Translational Science Support Core

The Nephrology Clinical Research Center (NCRC) offers a unique opportunity for kidney-focused clinical research, located adjacent to the Kidney Center Clinic and Dialysis Unit. The NCRC provides clinical space, equipment, standard protocols, an on-site biorepository, and professional staff to conduct patient-oriented studies, clinical trials, epidemiologic studies, and outcomes research. PhD-trained biostatisticians and data analysts dedicate time to support projects in the NCRC. We are excited to extend support to clinical research and data science projects conducted by our pre-and post-doctoral trainees within our IGNITE KUH training network and the UVA Nephrology fellowship program.

Our Core Mission is to improve the lives of people with kidney disease and advance scholarship in Nephrology and related fields by facilitating rigorous and relevant clinical research. Our portfolio of industry-oriented studies will help develop new treatments and diagnostics for kidney disease while providing our patients with opportunities to participate in trials. Our investigator-driven portfolio will pursue innovative research that answers fundamental questions in nephrology, translates existing knowledge into patient care, and inspires early-career faculty and trainees to pursue investigative careers.

National Partners in Kidney Disease Research
NCRC investigators have diverse research interests aimed at developing novel approaches to diagnosis, prevention, and treatment to improve the lives of patients with kidney disease. Our researchers actively participate in observational and interventional patient-oriented clinical studies, as well as data-oriented research. The NCRC portfolio includes national consortia projects, multicenter randomized clinical trials, and investigator-initiated translational and data studies; past and present topics include:

• Polycystic kidney disease
• Membranous nephropathy
• APOL1-mediated proteinuric kidney disease
• Diabetic nephropathy
• Cardiorenal syndrome
• Dialysis
• Kidney transplantation
• Hypertension
• Mineral Metabolism/Chronic Kidney Disease- Mineral and Bone Disorder
• Inflammation
• Sepsis
• Therapeutic Apheresis

See our Recent Publications here.

To access NCRC resources, please use your UVA email account with the subject line ‘study request’: nephcrc@virginia.edu. A brief REDCap registration survey will follow. Please do not include sensitive or detailed study information in your email inquiry.

Questions or external requests for collaboration can be sent to our Operational Director, Igor Shumilin, at ias2n@uvahealth.org.

We look forward to working with you!