Eduard E de Lange, MD


Eduard E. de Lange, MD

Professor of Radiology and Medical Imaging

Medical School, University of Leiden Medical School, Leiden, The Netherlands, 1973
Residency, Radiology, University of Leiden, The Netherlands, 1983

University of Virginia Hospital Medical Center
Department of Radiology and Medical Imaging
Box 800170
Charlottesville, VA 22908

(434) 924-1567

Research Interests

Hyperpolarized noble gas MR imaging of the lungs, Body MR imaging.

Research Lab

Hyperpolarized Gas MR Imaging


Ventilation-based segmentation of the lungs using hyperpolarized (3)He MRI. Tustison NJ, Avants BB, Flors L, Altes TA, de Lange EE, Mugler JP 3rd, Gee JC. J Magn Reson Imaging. 2011 Oct;34(4):831-41. doi: 10.1002/jmri.22738. Epub 2011 Aug 11.

Pulmonary kinematics from tagged hyperpolarized helium-3 MRI. Tustison NJ, Awate SP, Cai J, Altes TA, Miller GW, de Lange EE, Mugler JP 3rd, Gee JC. J Magn Reson Imaging. 2010 May;31(5):1236-41.

Assessment of the lung microstructure in patients with asthma using hyperpolarized 3He diffusion MRI at two time scales: comparison with healthy subjects and patients with COPD. Wang C, Altes TA, Mugler JP 3rd, Miller GW, Ruppert K, Mata JF, Cates GD Jr, Borish L, de Lange EE. J Magn Reson Imaging. 2008 Jul;28(1):80-8.

Rapid hyperpolarized 3He diffusion MRI of healthy and emphysematous human lungs using an optimized interleaved-spiral pulse sequence. Salerno M, Altes TA, Brookeman JR, de Lange EE, Mugler JP 3rd. J Magn Reson Imaging. 2003 May;17(5):581-8.

Hyperpolarized 3He MR lung ventilation imaging in asthmatics: preliminary findings.Altes TA, Powers PL, Knight-Scott J, Rakes G, Platts-Mills TA, de Lange EE, Alford BA, Mugler JP 3rd, Brookeman JR. J Magn Reson Imaging. 2001 Mar;13(3):378-84.

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