The Lung Transplant and Injury Research Lab in the Department of Surgery is comprised of a diverse team of clinicians, faculty, staff, and students dedicated to helping patients through the advancement of basic and translational research as well as providing research training to Residents, PostDocs, and Students. Our lab utilizes both in vivo and in vitro models to study clinically relevant issues including: mechanisms of lung ischemia-reperfusion injury after transplant, organ preservation, ex vivo lung perfusion (EVLP), in vivo lung perfusion (IVLP), dermal burn wounds, and organ injury after cardiopulmonary bypass.
Our research team (L-R): Alex Wisniewski, MD (Resident), Cindy Dodson (Senior Laboratory Specialist), Anthony Norman, MD (Resident), Autumn Rogers (Laboratory Specialist), Vic Laubach, PhD (Principle Investigator), Huy Ta, PhD (Research Assistant Professor), Ray Strobel, MD (Resident), Andy Young, MD (Resident).
Our lab has multiple research projects underway including: 1) role of TRPV4 and Piezo1 channels in lung ischemia-reperfusion injury (IRI) after transplant, 2) testing therapeutic strategies to prevent IRI, 3) vascular endothelial barrier, 4) reconditioning lungs via EVLP, and 5) IVLP-mediated attenuation of ARDS.
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