Current Studies

Current Studies
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Actively Recruiting

Glycemic Profiles and Insulin Delivery Across the Menstrual Cycle in Women with Type 1 Diabetes

Trial Title: Glycemic Profiles and Insulin Delivery Across the Menstrual Cycle in Women with Type 1 Diabetes
IRB-HSR#190046
PI: Chiara Fabris, PhD
RC: Lianna Smith

The Center for Diabetes Technology seeks women ages 18 to 40 with Type 1 Diabetes for a research study. The purpose of the study is find out how much the menstrual cycle effects the blood glucose variability and the effectiveness of insulin delivery. You may be eligible for this study if you are a woman who has had type 1 diabetes for at least 1 year, have used an insulin pump for at least 6 months, your A1c is under 8.5% (tested within 6 months), and have used a Continuous Glucose Monitor (CGM) in the last 6 months.

Your participation in this study will last about 3 months and involve about 5 visits. The first visit is a screening visit to determine the safety of your participation and includes a review of your medical history, a urine pregnancy test, and a physical exam. After the screening visit, you will be trained on the study equipment which includes a CGM and Activity Tracker. You will also be asked to track information about your cycle into an App, the amount of carbohydrate you consume each day, download your data on a regular basis and, if not using an oral contraceptive, perform ovulation tests. You will have check-in visits with study staff at least once a month. The final visit includes return of study equipment, a urine pregnancy test and a fingerstick A1c test.  Study visits may be completed in person or completed virtually.

Study-related supplies, exams, and A1c testing (if needed) provided free of charge. Compensation is provided.

For more information, please contact: Lianna Smith, lhs7px@hscmail.mcc.virginia.edu

Adapting Diabetes Treatment Expert Systems to Patient’s Expectations and Psychobehaviorla Characteristics in Type 1 Diabetes

Trial Title: Adapting Diabetes Treatment Expert Systems to Patient’s Expectations and Psychobehavioral Characteristics in  Type 1 Diabetes
IRB-HSR#200007
PI: Marc Breton
RC: Emma Emory

The Center for Diabetes Technology seeks adults ages 18 and up with type 1 diabetes for a research study. The purpose of this study is to test different ways CGM data can be used to help manage your diabetes.

You may be eligible for this study if you are currently using an insulin pump, your A1c is between 6.5% – 11%, and you have had type 1 diabetes for at least 1 year.

This study involves using a Tandem t:slim X2 pump, Dexcom G6 sensors, and an investigational diabetes application on an Android smart phone. There will be weekly surveys to complete, as well as 3 separate blood draws for A1c and lab values. This study will last approximately 7 months and there will be approximately 7 visits. Most of these visits will be completed virtually using a web-based video conferencing tool.

Study-related Dexcom G6 sensors, transmitters, and infusion sets will be provided free of charge.

For more information, please contact: Emma Emory, ee9m@hscmail.mcc.virginia.edu

 

Web-Based Simulation Tool for Type 1 Diabetes

Trial Title: Web-based simulation tool for self-management support in type 1 diabetes mellitus
IRB-HSR#200157
PI: Patricio Colmegna, PhD
RC: Ryan McFadden

The UVA Center for Diabetes Technology seeks adults aged 21-65 years for a research study. You may be eligible for this study if you have had type 1 diabetes for more than a year and wear a Tandem insulin pump.

The purpose of this study is to test a computer program that might give additional information to users with type 1 diabetes about their blood glucose control and insulin changes. The program does this by allowing users to simulate changes to their diabetes treatment decisions. The program then shows the possible blood glucose outcomes of those changes.

This study involves four visits within about 35 days. These visits may be held in-person at the Clinical Research Unit or may held via a secure web-based video conferencing tool. Visit 1 is a screening visit where a physician will make sure it is safe for you to participate. They may ask for a finger-stick HbA1c if you do not have one from within 3 months. Visit 2 involves taking two surveys and study device training. Visit 2 may be combined with Visit 1. You will be asked to interact with the computer program at least once a week for about 5 weeks. Then you will return for Visit 3 and will take two more surveys. Visit 4 will be a follow-up interview to ask about your experience using the program.

If needed, study-related point-of care lab tests, pregnancy test, and Dexcom G6 sensors and transmitter will be provided free of charge.

For more information, please contact: Ryan McFadden, rkm2f@hscmail.mcc.virginia.edu

 

Not Currently Enrolling

SGLT2 Inhibitor Adjunctive Therapy to Closed Loop Control in Type 1 Diabetes Mellitus

Closed to Enrollment

CloudConnect

International Diabetes Closed-Loop (iDCL) Trial, Clinical Acceptance of the Artificial Pancreas

Project Nightlight

Results Pending

Insulin- Glucose-Glucagon Network: Defining a Type 1 Diabetes Progression Index

The VRIF Trial: Hypoglycemia Reduction With Automated-Insulin Delivery System

A Study of t:Slim X2 With Control-IQ Technology (DCLP5)

Exercise-Induced Hypoglycemia Prevention in Adults With Type 1 Diabetes Using an Artificial Pancreas

Study to Test Efficacy of Real-time Reminders on Apple Watch To Decrease Late or Missed Meal Boluses

Efficacy of inControl Advice: A Decision Support System (DSS) for Diabetes

CGM Use in Islet Transplant Recipients

Exercise Activity-Based Bolus Decisions

Enhancement of Glucagon Counterregulation in Type 1 Diabetes by Basal Amylin Replacement

Feasibility of a Decision Support System to Reduce Glucose Variability in Subject With T1DM

USS Virginia Closed-Loop Versus SAP Therapy for Hypoglycemia Reduction in T1D

Dual Hormone

Completed Studies

Real-Time Monitoring and Glucose Control During Winter-Sport Exercise in Youth with Type 1 Diabetes: The AP Ski Camp Continued

Reducing Risks and Improving Glucose Control During Extended Exercise in Youth With T1DM: The AP Ski Camp

Closed-Loop Control in Young Children 5-8 Years Old Using DiAs Platform

At Home Study of a Zone-Model Predictive Control (MPC) Controller and a Health Monitoring System (HMS) With the Diabetes Assistant (DiAs) System and Run-to-Run Adaptation

Interested in Participating in a Trial?

Complete the form here to securely send your information to CDT staff.

Click Here