Helmy M. Siragy, MD, FACP, FAHA
PRIMARY APPOINTMENT
Professor of Medicine and Endocrinology
University of Virginia
Charlottesville, Virginia
CONTACT:
Helmy M. Siragy, M.D.
Department of Internal Medicine, Box 801409
University of Virginia Health System
450 Ray C Hunt Drive
Charlottesville, VA 22902
Office: (434) 924-5629
Lab: (434) 924-9661
Fax: (434) 982-3626
EDUCATION AND TRAINING
- Primary: Tanta University
- Residency: University of Texas
- Fellowships: University of Texas. University of Virginia
FUNDED PROJECTS
- NIH/NHLBI R01 HL09153518 (7/14/2017 – 6/30/2021)
- NIH/NHLBI R01 DK11487504 (8/17/2017 – 5/31/2021)
RESEARCH SUMMARY
Dr. Helmy M. Siragy developed the microdialysis technique, which led to a Golden Age of revolutionary discoveries about the nature of angiotensin receptors and renal paracrine hormones.
The lab focuses on the biology and pathophysiology of angiotensin subtype receptors in the cardiovascular system. Currently, the lab is conducting pioneering translational research that has a significant clinical impact and is related to cardiac ischemia, diabetic kidney disease, local tissue production of aldosterone, and its paracrine functions in the kidney and heart.
The Lab is also involved in clinical studies related to aldosterone pulse activity in normal individuals and patients with primary aldosteronism, vasopressin receptors in kidneys, and management of hyponatremia, and one of our ongoing studies investigating the effects of long-term angiotensin subtype one receptor blockade on cardiovascular morbidity and mortality.
Organizations Dr. Siragy is associated with: