6/17/2025
My lab is primarily focused on both understanding and manipulating cell-ECM mechanotransduction pathways in homeostasis and disease. Our primary interest is in understanding how cells' changing microenvironment direct their phenotype…
6/17/2025
Background and Summary of Previous Findings: Neural development involves competition at many levels, whether it be axons innervating a target or synapses refining a connection. Over 50 years ago, Viktor…
6/17/2025
Why do some animals have the ability to regenerate certain tissues and organs, while others have lost this capacity? The study of regenerative biology and medicine have shown that the…
6/17/2025
Introduction: Mitochondria are often pictured in biology texts as static, individual organelles, when in reality they form highly dynamic and mobile networks constantly undergoing fusion and fission. Research in the last…
6/17/2025
Research Description One of the major goals of my research program is to understand the role of membrane microdomains such as lipid rafts and caveolae in health and disease. We address…
6/17/2025
Human development, immunity, wound healing, fertility, and nutrient uptake all depend upon the ability of cells to change shape. Acquisition of an asymmetric or polarized morphology by a cell is…
6/17/2025
The long-term goal of our research program is to elucidate the roles of peripheral and central glia and glial-glial interactions during nervous system development, maintenance and disease/injury. Using Danio rerio…
6/17/2025
My lab is interested in epithelial homeostasis, secretion and innate defense. We focus on the human prosecretory mitogen 'lacritin' that we discovered and named out of an unbiased screen for…
6/17/2025
All the way up to the 20th century, the human genome has been optimized to survive in environments characterized by fluctuations between periods of feast and famine. These survivor-genomes clash…
6/17/2025
The Pani lab pursues curiosity-driven research exploring the cell biological foundations of development and tissue maintenance. Cell-cell signaling performs critical functions in development, homeostasis, and disease. In normal conditions, cell signaling…
