6/17/2025
Research: My research focuses on understanding the molecular basis of brain tumor development and growth and on using the acquired knowledge to identify new targets and develop new approaches for…
6/17/2025
The Agaisse Lab is associated with the Department of Microbiology, Immunology, and Cancer Biology (MIC). Our laboratory studies the bacterial pathogen Shigella flexneri, which causes approximately 270 million cases of…
6/17/2025
Research Projects Engineering T cells to overcome suppressive signals in the tumor microenvironment Engineered T cell therapy can effectively kill ovarian cancer cells, but there are still tumor-driven hurdles that T cells…
6/17/2025
My current research involves evaluation and improvement of techniques for sequencing DNA on lambda and BAC templates as part of programs of genome analysis. They are employed to elucidate genome…
6/17/2025
The survival of organisms ranging from simple bacteria to complex metazoans relies on the ability of individual cells to sample the environment and respond appropriately. Understanding the molecular pathways involved…
6/17/2025
6/17/2025
Project Title: Pathogenesis of Infections by Herpes Simplex Virus Herpes simplex virus is widespread in the human population with most people exposed during childhood. Nearly all adults have specific antibodies. HSV-1…
6/17/2025
Research description: Herpes simplex viruses type 1 and type 2 are significant human pathogens. Approximately 65% of the US population are infected with HSV-1 and 20% with HSV-2. The viruses persist…
6/17/2025
Our laboratory studies N. gonorrhoeae, an obligate human bacterial pathogen that causes the sexually transmitted infection gonorrhea. Gonorrhea has existed within the human population for all of recorded history and…
6/17/2025
We study the molecular mechanisms underlying the interaction between pathogens and their mammalian host. In particular, we investigate how the obligate intracellular bacteria Chlamydia trachomatis manipulates the host and establishes…
